Katherine C. Wood

University of Pittsburgh — United States

Medicine · Health Sciences

26h-index2.5kcitations74works0.42yr avg
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Research Topics

Hemoglobinopathies and Related Disorders(28), Nitric Oxide and Endothelin Effects(11), Heme Oxygenase-1 and Carbon Monoxide(10), Hemoglobin structure and function(10), Folate and B Vitamins Research(7)

Publications74 total

CYB5R3 Controls Sex-Specific Stress Erythropoiesis via Heme-Biosynthesis
2025
Impact of hematopoietic lineage-specific deletion of CYB5R3 on steady-state and stress erythropoiesis In Vivo
Blood·2025Open Access
Endothelial CYB5R3 couples store-operated calcium entry to TRPV2 activation and vascular fitness
2025Open Access
Abstract TMP120: CYB5R3 T117S Enlarges Cerebral Infarct Volume and Platelet Activation in Mice Subjected to Transient MCAO-induced Ischemic Stroke
Stroke·2025
Daprodustat Induces Fetal Hemoglobin and Erythropoietic Drive in an <i>in Vitro</i> and <i>In Vivo</i> Model of Sickle Cell Disease
Blood·2024· 1 citedOpen Access
Role of CYB5R3 in Erythropoiesis-Associated Heme Biosynthesis
Blood·2024· 1 citedOpen Access
CYB5R3 regulates endothelial store-operated Ca2+ signaling via NO-dependent mechanism
Free Radical Biology and Medicine·2024
CYB5R3 T117S tempers fetal hemoglobin induction by hydroxyurea in patients with sickle cell disease
Blood Advances·2024· 1 citedOpen Access
Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease
Redox Biology·2023· 13 citedOpen Access
Hemin and iron increase synthesis and trigger export of xanthine oxidoreductase from hepatocytes to the circulation
Redox Biology·2023· 22 citedOpen Access
Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies
Redox Biology·2023· 7 citedOpen Access
Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies
2023Open Access
Release of hepatic xanthine oxidase (XO) to the circulation is protective in intravascular hemolytic crisis
Redox Biology·2023· 13 citedOpen Access
Abstract 104: Cytochrome B5 Reductase 3 Regulates The Erythropoietin Response To Ischemic Stroke In A Mouse Model Of Chronic Anemia And Oxidative Stress
Stroke·2023
Loss of Cyb5R3 Function Silences Fetal Hemoglobin and Hematocrit Responses to Hydroxyurea in Patients with Sickle Cell Anemia
Blood·2022
Preclinical Development and Screening of a Quinone-Nitroalkene Molecule for Sickle Cell Anemia
Blood·2022
Inhibition of Hypoxia Inducible Factor Prolyl Hydroxylase By FG-4592 (Roxadustat) Increases Erythropoietic Stimulation in a Mouse Model of Sickle Cell Disease
Blood·2022· 1 cited
Cytochrome b5 reductases: Redox regulators of cell homeostasis
Journal of Biological Chemistry·2022· 59 citedOpen Access
Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death
Journal of Clinical Investigation·2022· 18 citedOpen Access
SOD2 V16A Amplifies Vascular Dysfunction in Sickle Cell Patients by Curtailing Mitochondria Complex IV Activity
Free Radical Biology and Medicine·2022· 2 cited
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Frequent Co-authors

Adam C. Straub(26), Scott Hahn(13), D. Neil Granger(11), Shuai Yuan(11), Mark T. Gladwin(9), Heidi M. Schmidt(9), Janice Russell(7), Robert Brink(6), Megan Miller(6), Francisco J. Schöpfer(6), Karen Y. Stokes(6), Sruti Shiva(6), Darío A. Vitturi(6), Eric E. Kelley(5), Subramaniam Sanker(5), Brittany G. Durgin(5), Atinuke Dosunmu-Ogunbi(5), Jeffrey Baust(5), Dominique Gatto(4), Robert P. Hebbel(4)