Salil N. Pendse

Computer Science · Physical Sciences

14h-index470citations32works0.02yr avg
OpenAlex↗Google Scholar↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Computational Drug Discovery Methods(7), Carcinogens and Genotoxicity Assessment(6), Helicobacter pylori-related gastroenterology studies(5), Pharmacogenetics and Drug Metabolism(5), Effects and risks of endocrine disrupting chemicals(5)

Publications32 total

Physiologically Based Pharmacokinetic (PBPK) modeling of hepatic impairment using PK-Sim
2024Open Access
Physiologically‐based pharmacokinetic modelling to predict intragastric rifabutin concentrations in the treatment of <i>Helicobacter pylori</i> infection
Alimentary Pharmacology & Therapeutics·2023· 9 citedOpen Access
S1597 Modeling Gastric Luminal Rifabutin Concentrations: RHB-105 (Rifabutin 50 mg Q8H) Provides More Favorable Exposure for Helicobacter pylori Eradication Than Generic Rifabutin 150 mg BID or 300 mg QD
The American Journal of Gastroenterology·2022
Tu1077: PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO ESTIMATE INTRAGASTRIC RIFABUTIN CONCENTRATIONS FOLLOWING RIFABUTIN 50 MG Q8H (RHB-105) OR 150 MG QD: MORE FAVORABLE EXPOSURE FOR HELICOBACTER PYLORI ERADICATON WITH Q8H DOSING
Gastroenterology·2022
Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation
Frontiers in Toxicology·2022· 20 citedOpen Access
S1417 RHB-105 Q8H Rifabutin Dosing Provides Favorable Exposure for Helicobacter pylori Eradication
The American Journal of Gastroenterology·2021
RNA-sequencing (transcriptomic) data collected in liver and lung of male and female B6C3F1 mice exposed to various dose levels of 4-methylimidazole for 2, 5, or 28 days
Data in Brief·2021· 4 citedOpen Access
Population Life Course Exposure to Health Effects Modeling [R package plethem version 1.1.0]
2020
The TTC Data Mart: An interactive browser for threshold of toxicological concern calculations
Computational Toxicology·2020· 3 citedOpen Access
Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids
Toxicological Sciences·2020· 11 citedOpen Access
Physiologically based pharmacokinetic modeling software
Elsevier eBooks·2020· 10 cited
P130 - Evaluation of potential early-life sensitivity using life-stage physiologically based pharmacokinetics modeling with in vitro to in vivo extrapolation
Drug Metabolism and Pharmacokinetics·2020
Population Life-course exposure to health effects model (PLETHEM): An R package for PBPK modeling
Computational Toxicology·2019· 19 cited
Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods
Toxicology in Vitro·2019· 26 citedOpen Access
Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans
Toxicological Sciences·2019· 47 citedOpen Access
Addressing systematic inconsistencies between in vitro and in vivo transcriptomic mode of action signatures
Toxicology in Vitro·2019· 24 citedOpen Access
Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system
Toxicology in Vitro·2018· 13 citedOpen Access
Incorporation of public exposure models into the PLETHEM pharmacokinetic framework
Toxicology Letters·2018
Application of transcriptomic data, visualization tools and bioinformatics resources for informing mode of action
Current Opinion in Toxicology·2018· 16 cited
Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment
Regulatory Toxicology and Pharmacology·2018· 18 citedOpen Access
page 1 of 2Next →

Frequent Co-authors

Patrick D. McMullen(19), Melvin E. Andersen(16), Harvey J. Clewell(11), Michael B. Black(10), Miyoung Yoon(9), Rebecca A. Clewell(9), Alina Efremenko(8), Marjory Moreau(6), Pankajini Mallick(5), Darol E. Dodd(4), Chantel I. Nicolas(4), Colin W. Howden(4), Kely L. Sheldon(4), James S. Bus(3), Chad Deisenroth(3), Kamel Mansouri(3), Saad Haider(3), Michael Rosenberg(3), Rick A. Fasani(3), Thomas Härtung(3)