Nicholas P. West

University of Leeds — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index4.6kcitations153works4.62yr avg
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Research Topics

Gut microbiota and health(31), Exercise and Physiological Responses(25), Asthma and respiratory diseases(16), Probiotics and Fermented Foods(14), Muscle metabolism and nutrition(14)

Publications152 total

FOxTROT: Predictive effects of <i>ERBB2</i> and <i>ERBB3</i> on neoadjuvant panitumumab benefit in <i>RAS/BRAF</i> wild-type (-wt) locally advanced colon cancer (LACC).
Journal of Clinical Oncology·2026
AI-powered immune profiling from histopathology slides for chemo-radiotherapy outcome prediction in rectal cancer: a study using clinical trial and real-world cohorts
EBioMedicine·2025· 1 citedOpen Access
Technological advances in the search for a <scp>CURE</scp> for asthma
The Medical Journal of Australia·2025
Multi-omic spatial profiling of nasal polyps identifies multiple immune-epithelial cell-ligand receptor interactions 4292
The Journal of Immunology·2025Open Access
Late Breaking Abstract - CosMx™ subcellular spatial molecular imaging of bronchial biopsies from patients with severe eosinophilic asthma treated with mepolizumab. Preliminary results of the MESILICO study.
2025
Safety tolerability and proof of pharmacology of a dry powder formulation of the antiviral host defense enhancer INNA-051 in healthy adults aged 18-80
2025
Spatial profiling reveals complex cellular responses of anti-IL5 treatment with mepolizumab in eosinophilic chronic rhinosinusitis with nasal polyposis
Journal of Leukocyte Biology·2025Open Access
0465 Spatial profiling identifies distinct patterns of immune modulation with dupilumab in the dermis and epidermis of atopic dermatitis patients with improved quality of life
Journal of Investigative Dermatology·2025Open Access
Intranasal delivery of engineered anti-SARS-CoV-2 extracellular vesicles therapeutically represses lung infection and inflammation
Drug Delivery and Translational Research·2025· 2 citedOpen Access
1913 Tumour-to-stroma ratio identified by artificial intelligence impacts cancer outcomes in a phase III randomised rectal chemo-radiotherapy trial
Radiotherapy and Oncology·2025
1489 STAR-TREC (NCT02945566): A randomised phase II/III trial of CRT versus 5x5 Gy SCRT for organ preservation in early/intermediate risk rectal cancer
Radiotherapy and Oncology·2025· 6 cited
Spatial Transcriptomics Reveals Novel Mechanisms Involved in Perineural Invasion in Pancreatic Ductal Adenocarcinomas
Cancers·2025· 6 citedOpen Access
Priming mucosal pathogen-agnostic innate immunity with an intranasal TLR2/6 agonist in an aged population
ERJ Open Research·2025· 1 citedOpen Access
Spatial profiling reveals complex inflammatory responses of anti-IL5 treatment with mepolizumab in eosinophilic chronic rhinosinusitis with nasal polyposis
2024Open Access
Interleukin‐5 as a pleiotropic cytokine orchestrating airway type 2 inflammation: Effects on and beyond eosinophils
Allergy·2024· 43 citedOpen Access
The effect of Proteinase K treatment on GeoMx digital spatial profiling data quality from formalin-fixed, paraffin-embedded tissue
Pathology·2024· 3 citedOpen Access
LB951 Dupilumab treatment causes normalization of neuroimmune mediator gene and protein expression in the skin of Atopic Dermatitis
Journal of Investigative Dermatology·2024Open Access
Molecular analysis of human tick-bitten skin yields signatures associated with distinct spatial and temporal trajectories - A proof-of-concept study
Heliyon·2024· 2 citedOpen Access
Circulating TMAO, the gut microbiome and cardiometabolic disease risk: an exploration in key precursor disorders
Diabetology & Metabolic Syndrome·2024· 7 citedOpen Access
Erdosteine in children and adults with bronchiectasis (BETTER trial): study protocol for a multicentre, double-blind, randomised controlled trial
BMJ Open Respiratory Research·2024· 4 citedOpen Access
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Frequent Co-authors

Allan W. Cripps(25), Amanda J. Cox(17), David B. Pyne(17), Ping Zhang(8), Shona L. Halson(8), Peter Fricker(6), David T. Martin(6), Louise M. Burke(5), Gus Koerbin(5), Will G. Hopkins(4), Peggy L. Horn(4), Candice Colbey(4), Annabelle M. Watts(4), Alex E. Mohr(3), Jeremy R. Townsend(3), Katherine Black(3), Jamie Pugh(3), C. Christophersen(3), Michael A. Conlon(3), Sampo J. Lahtinen(3)