Sylvia Großklaus

University Hospital Carl Gustav Carus — Germany

Medicine · Health Sciences

15h-index959citations31works3.52yr avg
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Research Topics

Cell Adhesion Molecules Research(6), Immune Response and Inflammation(4), Erythrocyte Function and Pathophysiology(4), Adrenal Hormones and Disorders(4), Neuroinflammation and Neurodegeneration Mechanisms(3)

Publications31 total

A DEL-1/αvβ3 integrin axis promotes brown adipocyte progenitor proliferation and cold-induced brown adipose tissue adaptation
Molecular Metabolism·2025· 1 citedOpen Access
A key role of polyamine metabolism in adipose tissue homeostasis that regulates obesity
Metabolism·2025· 1 citedOpen Access
AZIN2-dependent polyamine metabolism determines adipocyte progenitor fate and protects against obesity and dysmetabolism
2024· 2 citedOpen Access
Formyl peptide receptor 2 regulates dendritic cell metabolism and Th17 cell differentiation during neuroinflammation
Frontiers in Immunology·2024· 10 citedOpen Access
Supplementary Methods, Figures 1-9 from A Novel Function of Junctional Adhesion Molecule-C in Mediating Melanoma Cell Metastasis
2023Open Access
Data from A Novel Function of Junctional Adhesion Molecule-C in Mediating Melanoma Cell Metastasis
2023Open Access
Supplementary Methods, Figures 1-9 from A Novel Function of Junctional Adhesion Molecule-C in Mediating Melanoma Cell Metastasis
2023Open Access
Data from A Novel Function of Junctional Adhesion Molecule-C in Mediating Melanoma Cell Metastasis
2023Open Access
Stromal cell–derived DEL-1 inhibits Tfh cell activation and inflammatory arthritis
Journal of Clinical Investigation·2021· 24 citedOpen Access
Glycolysis is integral to histamine‐induced endothelial hyperpermeability
The FASEB Journal·2021· 20 citedOpen Access
DHEA Inhibits Leukocyte Recruitment through Regulation of the Integrin Antagonist DEL-1
The Journal of Immunology·2020· 28 citedOpen Access
53BP1 Deficiency Promotes Pathological Neovascularization in Proliferative Retinopathy
Thrombosis and Haemostasis·2019· 5 cited
DEL-1 promotes macrophage efferocytosis and clearance of inflammation
Nature Immunology·2018· 294 citedOpen Access
Endothelial Cell–Specific Overexpression of Del-1 Drives Expansion of Haematopoietic Progenitor Cells in the Bone Marrow
Thrombosis and Haemostasis·2018· 18 cited
DHEA inhibits acute microglia-mediated inflammation through activation of the TrkA-Akt1/2-CREB-Jmjd3 pathway
Molecular Psychiatry·2017· 97 cited
Hes3 expression in the adult mouse brain is regulated during demyelination and remyelination
Brain Research·2016· 6 citedOpen Access
Milk Fat Globule-Epidermal Growth Factor 8 (MFG-E8) Is a Novel Anti-inflammatory Factor in Rheumatoid Arthritis in Mice and Humans
Journal of Bone and Mineral Research·2015· 58 citedOpen Access
Brief Report: Endothelial‐Specific X‐Box Binding Protein 1 Deficiency Limits Tumor Necrosis Factor–Induced Leukocyte Recruitment and Vasculitis
Arthritis & Rheumatology·2015· 18 cited
Loss of milk fat globule-epidermal growth factor 8 (MFG-E8) in mice leads to low bone mass and accelerates ovariectomy-associated bone loss by increasing osteoclastogenesis
Bone·2015· 27 cited
The role of hematopoietic TLR-signaling in sepsis-associated adrenal inflammation and the HPA axis activation
Experimental and Clinical Endocrinology & Diabetes·2015
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Frequent Co-authors

Triantafyllos Chavakis(19), Kyoung‐Jin Chung(7), George Hajishengallis(7), Maria Troullinaki(6), Vasileia Ismini Alexaki(6), Stefan R. Bornstein(6), Valeria V. Orlova(6), Gustavo Baretton(6), David Sprott(6), Triantafyllos Chavakis(6), Aleš Neuwirth(5), Waldemar Kanczkowski(5), Harald F. Langer(5), Changping Xie(5), Sunil C. Kaul(5), Darius Schneider(5), Anke S. Lonsdorf(5), Manuela Fahrleitner(5), Eun Young Choi(5), Vanessa Dutoit(5)