Hiddo J.L. Heerspink

University Medical Center Groningen — Netherlands

Medicine · Health Sciences

117h-index61.7kcitations1.1kworks7.62yr avg
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Research Topics

Diabetes Treatment and Management(570), Chronic Kidney Disease and Diabetes(360), Pancreatic function and diabetes(160), Blood Pressure and Hypertension Studies(159), Diabetes Management and Research(131)

Publications1.1k total

Urinary clusterin as a biomarker of human kidney disease progression and response to the endothelin receptor antagonist atrasentan: An exploratory analysis from the SONAR trial
Nature Communications·2026Open Access
Efficacy, Mechanisms, and Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Kidney Transplant Recipients
Clinical Journal of the American Society of Nephrology·2025· 1 cited
Cardiovascular-Kidney Effects of Dapagliflozin in Patients at Cardiovascular Risk With or Without Type 2 Diabetes: Results of a Randomized, Double-Blind, Placebo-Controlled Trial
Hypertension·2025
Inhibition of IL-33 in Diabetic Kidney Disease
Journal of the American Society of Nephrology·2025
Cardiac impact of dapagliflozin in advanced chronic kidney disease: rationale and design of the Renal Lifecycle Trial cardiac imaging sub-studies
Clinical Kidney Journal·2025Open Access
Baseline Risk and Longitudinal Changes in kidneyintelX.dkd and Its Association With Kidney Outcomes in the CANVAS and CREDENCE Trials
Diabetes Care·2025Open Access
SGLT2 Inhibitors and Kidney Outcomes by Glomerular Filtration Rate and Albuminuria
JAMA·2025· 6 citedOpen Access
Effects of Sodium Glucose Cotransporter 2 Inhibitors by Diabetes Status and Level of Albuminuria
JAMA·2025· 5 citedOpen Access
Baseline Kidney Function, Albuminuria, and Urine Albumin-Creatinine Ratio Reduction with Finerenone, Empagliflozin, or Both
Journal of the American Society of Nephrology·2025· 1 citedOpen Access
A meta-analysis of albuminuria as a surrogate endpoint for kidney failure
Nature Medicine·2025· 2 cited
Proteinuria or Albuminuria as Markers of Kidney and Cardiovascular Disease Risk
Annals of Internal Medicine·2025Open Access
Balcinrenone in combination with dapagliflozin compared with dapagliflozin alone in patients with chronic kidney disease and albuminuria: a randomised, active-controlled double-blind, phase 2b clinical trial
The Lancet·2025· 4 citedOpen Access
Rationale, design and baseline characteristics of the TRANSCEND-CKD trial of retatrutide in patients with chronic kidney disease
Nephrology Dialysis Transplantation·2025Open Access
Proteins and signalling pathways targeted by dapagliflozin and finerenone: Insights from <scp>DAPA</scp> ‐ <scp>CKD</scp> and <scp>FIGARO</scp> ‐ <scp>DKD</scp>
Diabetes Obesity and Metabolism·2025· 1 citedOpen Access
&lt;b&gt;Dickkopf-3 (DKK3) &lt;/b&gt;&lt;b&gt;and the progression of diabetic kidney disease&lt;/b&gt;&lt;b&gt;in primary health care&lt;/b&gt;
2025Open Access
&lt;b&gt;Dickkopf-3 (DKK3) &lt;/b&gt;&lt;b&gt;and the progression of diabetic kidney disease&lt;/b&gt;&lt;b&gt;in primary health care&lt;/b&gt;
2025Open Access
DMX-200 in Patients With Primary Focal Segmental Glomerulosclerosis: Results of the Phase 2 ACTION2 Trial
Kidney International Reports·2025· 1 citedOpen Access
Dickkopf-3 (DKK3) and the Progression of Diabetic Kidney Disease in Primary Health Care
Diabetes·2025· 4 citedOpen Access
Randomized trials in cardiovascular, kidney, and metabolic diseases: rethinking late-phase drug development
European Heart Journal·2025
Risk of CKD Progression in a Real-World Population Eligible for the ZENITH-High Proteinuria Trial
Journal of the American Society of Nephrology·2025
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Frequent Co-authors

Vlado Perkovic(17), Dick de Zeeuw(15), Tom Greene(11), David C. Wheeler(11), Ron T. Gansevoort(10), Josef Coresh(9), Meg Jardine(8), Adeera Levin(8), Peter Rossing(8), Bruce Neal(7), John J.V. McMurray(7), Christoph Wanner(7), Barry M. Brenner(6), Ricardo Correa‐Rotter(6), Fan Fan Hou(6), Kunihiro Matsushita(6), Robert G. Nelson(6), David Z.I. Cherney(6), Katherine R. Tuttle(6), Andrew S. Levey(6)