Karthik Selvaraju

Linköping University — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index1.5kcitations30works1.72yr avg
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Research Topics

Ubiquitin and proteasome pathways(15), Chemokine receptors and signaling(8), Histone Deacetylase Inhibitors Research(7), Immunotherapy and Immune Responses(5), Glycosylation and Glycoproteins Research(3)

Publications30 total

Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
eLife·2024· 8 citedOpen Access
Author response: Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
2024Open Access
Author response: Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
2024Open Access
Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
2024Open Access
Loss of the proteasomal deubiquitinase USP14 induces growth defects and a senescence phenotype in colorectal cancer cells
Scientific Reports·2024· 2 citedOpen Access
Author Response: Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
2024Open Access
Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
2024Open Access
Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
eLife·2024· 2 citedOpen Access
New Approach to Underwater Image Enhancement Using Modified Residual Blocks in Generator Architecture for Improved Cycle Generative Adversarial Networks
Proceedings of the Bulgarian Academy of Sciences·2024· 3 citedOpen Access
Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
2023· 1 citedOpen Access
Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action
Frontiers in Oncology·2022· 6 citedOpen Access
Sensitivity of Acute Myelocytic Leukemia Cells to the Dienone Compound VLX1570 Is Associated with Inhibition of the Ubiquitin-Proteasome System
Biomolecules·2021· 5 citedOpen Access
Identification of proteasome inhibitors using analysis of gene expression profiles
European Journal of Pharmacology·2020· 19 citedOpen Access
Induction of ER Stress in Acute Lymphoblastic Leukemia Cells by the Deubiquitinase Inhibitor VLX1570
International Journal of Molecular Sciences·2020· 14 citedOpen Access
Author Correction: Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system
Scientific Reports·2019· 1 citedOpen Access
Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15
PLoS ONE·2019· 12 citedOpen Access
Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system
Scientific Reports·2019· 34 citedOpen Access
Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug
Biochimie·2019· 162 cited
Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation
Cancer Letters·2019· 28 cited
Abstract 2795: Screening and characterization of drugs that inhibit the ubiquitin-proteasome system
Cancer Research·2018
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Frequent Co-authors

Pádraig D’Arcy(15), Stig Linder(14), Eva M. García‐Cuesta(8), Pablo Martínez(8), Adrián Miguel Gómez Pozo(8), Gianluca D’Agostino(8), Sofía R. Gardeta(8), Adriana Quijada‐Freire(8), Patricia Blanco Gabella(8), Carlos Roca(8), Rodrigo Jiménez‐Saiz(8), Alfonso García‐Rubia(8), Pilar Lucas(8), Rosa Ayala-Bueno(8), Noelia Santander Acerete(8), Yolanda R. Carrasco(8), Ana Martı́nez(8), Nuria E. Campillo(8), José Miguel Rodríguez‐Frade(8), César Santiago(8)