Chul‐Seung Park

Gwangju Institute of Science and Technology — South Korea

Biochemistry, Genetics and Molecular Biology · Life Sciences

33h-index3.9kcitations153works1.12yr avg
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Research Topics

Ion channel regulation and function(56), Protein Degradation and Inhibitors(32), Cardiac electrophysiology and arrhythmias(23), Histone Deacetylase Inhibitors Research(22), Neuroscience and Neuropharmacology Research(19)

Publications153 total

Cereblon promotes influenza virus replication through AMPK ubiquitination
2025Open Access
0289 Cereblon Deficiency Increases AMP-Activated Kinase and Homeostatic Sleep Response Mice
SLEEP·2025Open Access
Discovery of Diphenyl Ether Derivatives as Novel BK<sub>Ca</sub> Channel Activators: Structure-Activity Relationship, Cryo-EM Complex Structures, and <i>In Vivo</i> Animal Studies
Journal of Medicinal Chemistry·2025
Cereblon regulates the production of hepatic fibroblast growth factor 23 in diabetes
BMB Reports·2024Open Access
CRBN modulates synuclein fibrillation via degradation of DNAJB1 in mouse model of Parkinson disease
npj Parkinson s Disease·2024· 1 citedOpen Access
Enhanced homeostatic sleep response and decreased neurodegenerative proteins in cereblon knock-out mice
Communications Biology·2024· 4 citedOpen Access
The cereblon-AMPK (AMP-activated protein kinase) axis in chondrocytes regulates the pathogenesis of osteoarthritis
Osteoarthritis and Cartilage·2024· 3 citedOpen Access
Activation mechanism and novel binding sites of the BK<sub>Ca</sub>channel activator CTIBD
Life Science Alliance·2024· 2 citedOpen Access
Discovery and mechanistic studies of a novel BK<sub>Ca</sub> channel modulator inducing long openings
Physiology·2024
Enhancement of the SESN2-SHP cascade by melatonin ameliorates hepatic gluconeogenesis by inhibiting the CRBN-BTG2-CREBH signaling pathway
Experimental & Molecular Medicine·2023· 9 citedOpen Access
0024 Decreased circadian period associated with enhanced autophagy in cereblon knockout mice
SLEEP·2023· 1 citedOpen Access
Abstract LB157: Cereblon inhibits prostate cancer progression and metastasis by negatively regulating 6PGD
Cancer Research·2023
Effects of cereblon on stress-activated redox proteins and core behavior
Brain Research·2022· 4 cited
Comparative analysis of dermal collagen and lipids in cereblon ablated mice using a multimodal nonlinear optical system
Journal of Biophotonics·2022
Novel Thioxothiazolo[3,4-<i>a</i>]quinazolin-5(4<i>H</i>)-one Derivatives as BK<sub>Ca</sub> Channel Activators for Urinary Incontinence
ACS Medicinal Chemistry Letters·2022· 4 citedOpen Access
Discovery and characterization of a potent activator of the BKCa channel that relives overactive bladder syndrome in rats
European Journal of Pharmacology·2022· 2 cited
Cereblon contributes to cardiac dysfunction by degrading Cav1.2α
European Heart Journal·2022· 13 cited
Sophora flavescens Extracts Have Therapeutic Effects on Overactive Bladder Syndrome by Potentiation of Large-Conductance Calcium-Activated Potassium Channel
Natural Product Sciences·2021Open Access
Cereblon: promise and challenges for combating human diseases
Pflügers Archiv - European Journal of Physiology·2021· 13 cited
Regulation of AMPK Activity by CRBN Is Independent of the Thalidomide-CRL4CRBN Protein Degradation Axis
Pharmaceuticals·2021· 4 citedOpen Access
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Frequent Co-authors

Kwang Min Lee(7), Yong‐Chul Kim(6), Soo Hyun Eom(5), Hyun–Ho Lim(5), Tal Soo Ha(5), Kwan‐Young Jung(5), Heun Soh(4), Seung‐Joo Yang(4), Woo Keun Song(3), Joohong Ahnn(3), Yong Deuk Kim(3), Sungkwon Chung(3), Seong‐Hwan Rho(3), Changsoo Kim(2), Thang Van Nguyen(2), Raymond J. Deshaies(2), Christopher Miller(2), Jiyeon Lee(2), Do Han Kim(2), Jaya Bandyopadhyay(2)