Akhouri Kishore Raghawan

Biochemistry, Genetics and Molecular Biology · Life Sciences

4h-index105citations12works2.32yr avg
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Research Topics

Inflammasome and immune disorders(6), Heat shock proteins research(3), IL-33, ST2, and ILC Pathways(3), Epigenetics and DNA Methylation(2), Genetic Neurodegenerative Diseases(2)

Publications12 total

Chemical Perturbations Impacting Histone Acetylation Govern Colorectal Cancer Differentiation
Gastroenterology·2025· 2 cited
Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma
Cell Reports Medicine·2025· 4 citedOpen Access
Chemical perturbations impacting histone acetylation govern colorectal cancer differentiation
2024· 1 citedOpen Access
Cold-induced loss of interaction with HSC70 triggers inflammasome activity of familial cold autoinflammatory syndrome-causing mutants of NLRP3
Biochemical and Biophysical Research Communications·2022· 5 cited
Cold-induced loss of interaction with HSC70 triggers inflammasome activity of familial cold autoinflammatory syndrome-causing mutants of NLRP3
2022Open Access
Autophagy-independent cytoprotection by optineurin from toxicity of aggregates formed by mutant huntingtin and mutant ataxin-3
The Journal of Biochemistry·2022· 9 cited
HSC70 as a sensor of low temperature: role in cold‐triggered autoinflammatory disorders
FEBS Journal·2021· 4 cited
Complex formation and reciprocal regulation between GSK3β and C3G
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2021· 3 cited
Optineurin promotes aggregation of mutant huntingtin and mutant ataxin-3, and reduces cytotoxicity of aggregates
2020Open Access
HSC70 regulates cold-induced caspase-1 hyperactivation by an autoinflammation-causing mutant of cytoplasmic immune receptor NLRC4
Proceedings of the National Academy of Sciences·2019· 27 cited
HSC70 regulates cold-induced caspase-1 hyperactivation by an autoinflammation-causing mutant of cytoplasmic immune receptor NLRC4
2019· 2 citedOpen Access
A Disease-associated Mutant of NLRC4 Shows Enhanced Interaction with SUG1 Leading to Constitutive FADD-dependent Caspase-8 Activation and Cell Death
Journal of Biological Chemistry·2017· 48 citedOpen Access

Frequent Co-authors

G. Swarup(8), Vegesna Radha(5), Rajashree Ramaswamy(5), Zhixin Li(3), Nilay S. Sethi(3), Shivranjani C Moharir(2), Pornlada Likasitwatanakul(2), Khoa Doan(2), Sándor Spisák(2), Qi Liu(2), Priscilla Liow(2), Sunwoo Lee(2), David J. Chen(2), Pratyusha Bala(2), Pranshu Sahgal(2), Daulet Aitymbayev(2), Jennifer S. Thalappillil(2), Malvina Papanastasiou(2), William Hawkins(2), Steven A. Carr(2)