Lakshay Malhotra

University of Delhi — India

Medicine · Health Sciences

8h-index148citations30works1.52yr avg
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Research Topics

Cancer-related Molecular Pathways(9), Ubiquitin and proteasome pathways(5), Epigenetics and DNA Methylation(4), Cancer, Hypoxia, and Metabolism(4), RNA Research and Splicing(2)

Publications30 total

Targeting ubiquitin-specific protease 14 reduces metastatic potential and metabolic activity in cervical cancer via direct modulation of monocarboxylate transporter-4
Journal of Translational Medicine·2025Open Access
Dual Preconditioned Mesenchymal Stem Cells-Derived Culture Conditioned Media Augment Immunomodulation and Drive Metabolic Reprogramming in Acute Graft-versus-Host Disease
2025Open Access
Development of a novel anti BCMA (B cell Maturation Antigen) 9C4 academic CAR as a low cost adaptive cellular therapy candidate in multiple myeloma 2630
The Journal of Immunology·2025Open Access
1170 Development of a novel economical anti-BCMA antibody for targeted therapeutic intervention in multiple myeloma
Regular and Young Investigator Award Abstracts·2025Open Access
Biophysical and molecular characterization of HuR inhibitors, CMLD-2 and Dihydrotanshinone I (DHTS), in Triple Negative Breast Cancer (TNBC)
International Journal of Biological Macromolecules·2025· 3 cited
Unraveling the unique amyloid-like aggregation behavior of the tumor suppressor p53 mutants in human cancers
International Journal of Biological Macromolecules·2025
Immunogenicity and Structure of stabilized HIV-1 Clade-C Env from pediatric Elite-neutralizer complexed with autologous bNAb
2025Open Access
Abstract 1429: Ubiquitin specific peptidase 37 facilitate prostate cancer oncogenesis by regulation replication stress
Cancer Research·2025
Abstract 5574: Exploring the therapeutic potential of USP14 in cervical cancer: mechanisms of oncogenesis and metabolic regulation
Cancer Research·2025· 1 cited
The R337C mutation in the p53 oligomerization domain affects the regulatory domain and its ability to bind response elements: Evidence based on structural and biophysical studies
Archives of Biochemistry and Biophysics·2025
Hypoxia-Mediated Molecular Interactions of Tissue-Specific Mesenchymal Stem Cells Drive Metabolic Reprogramming and Immunomodulation in Acute Graft-versus-Host Disease
2025· 3 cited
Effect of phytosome complex of phosphatidylcholine and silymarin on broiler growth performance and carcass traits in broilers
International Journal of Veterinary Sciences and Animal Husbandry·2025Open Access
Phenotypical mapping of TP53 unique missense mutations spectrum in human cancers
Journal of Biomolecular Structure and Dynamics·2024· 3 cited
Bergenin inhibits growth of human cervical cancer cells by decreasing Galectin-3 and MMP-9 expression
Scientific Reports·2024· 13 citedOpen Access
Abstract 1830: Bergenin inhibits growth of human cervical cancer cells by decreasing galectin-3 and MMP-9 expression
Cancer Research·2024· 2 cited
Abstract 4639: Unraveling the oncogenic network of USP37 and USP14 in gynecological cancers: Decrypting the molecular landscape of chemoresistance
Cancer Research·2024
Comprehensive amino acid composition analysis of seed storage proteins of cereals and legumes: identification and understanding of intrinsically disordered and allergenic peptides
Journal of Biomolecular Structure and Dynamics·2024Open Access
Flavonoids as potential reactivators of structural mutation p53Y220C by computational and cell-based studies
Journal of Biomolecular Structure and Dynamics·2023· 6 cited
Ubiquitin specific peptidase 37 and PCNA interaction promotes osteosarcoma pathogenesis by modulating replication fork progression
Journal of Translational Medicine·2023· 11 citedOpen Access
Abstract 335: Ubiquitin Specific Peptidase 37<i>promotes Osteosarcoma oncogenesis by interacting with PCNA and impacting constitutive replication fork movement.</i>
Cancer Research·2023
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Frequent Co-authors

A.S. Ethayathulla(19), Gunjan Dagar(10), Punit Kaur(9), Mayank Singh(7), Ashna Gupta(7), Muzafar A. Macha(6), Shahab Uddin(5), Ajaz A. Bhat(5), Gururao Hariprasad(4), Ravi Chauhan(4), Ammira Al‐Shabeeb Akil(4), Ranjit Kumar Sahoo(4), Alankrita Singh(4), Ravi Chauhan(4), Saurabh Sharma(3), Vandana Mishra(3), Radhey Shyam Sharma(3), Ashna Gupta(3), Tariq Masoodi(3), Atul Batra(3)