Amanda Heard

The University of Kansas Cancer Center — United States

Medicine · Health Sciences

8h-index944citations22works1.22yr avg
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Research Topics

CAR-T cell therapy research(8), RNA Research and Splicing(4), Cancer Immunotherapy and Biomarkers(3), Acute Myeloid Leukemia Research(3), Silicon Carbide Semiconductor Technologies(3)

Publications22 total

Progesterone receptor-dependent downregulation of MHC class I promotes tumor immune evasion and growth in breast cancer.
UNC Libraries·2025Open Access
BACH2 regulates T cell lineage states to overcome dysfunction driven by tonic CAR signaling
Blood·2025· 1 citedOpen Access
Progesterone receptor-dependent downregulation of MHC class I promotes tumor immune evasion and growth in breast cancer
Journal for ImmunoTherapy of Cancer·2025· 3 citedOpen Access
BACH2 regulates T cell lineage states to overcome dysfunction driven by tonic CAR signaling
2025· 1 citedOpen Access
Site-specific O-GlcNAcylation of progesterone receptor (PR) supports PR attenuation of interferon stimulated genes (ISGs) and tumor growth in breast cancer
Journal of Biological Chemistry·2024· 2 citedOpen Access
Abstract 6877: Progesterone promotes immunosuppression in the murine mammary gland by causing T cell death
Cancer Research·2024
Regulation of the Transcriptional Repressor BACH2 Overcomes Tonic Signaling-Driven CAR T Cell Dysfunction
Blood·2023· 1 citedOpen Access
Costimulatory domains direct distinct fates of CAR-driven T cell dysfunction
Blood·2023· 49 citedOpen Access
Costimulatory domains direct distinct fates of CAR-driven T cell dysfunction
2023· 19 citedOpen Access
Costimulatory Domains Direct Distinct Fates of CAR T Cell Dysfunction
Blood·2022
Antigen glycosylation regulates efficacy of CAR T cells targeting CD19
Nature Communications·2022· 62 citedOpen Access
Antigen Glycosylation Is a Central Regulator of CAR T Cell Efficacy
Blood·2021· 2 cited
U2af1 is a haplo-essential gene required for hematopoietic cancer cell survival in mice
Journal of Clinical Investigation·2021· 17 citedOpen Access
Advances in CAR design
Best Practice & Research Clinical Haematology·2021· 5 cited
<i>U2AF1</i> is a haplo-essential gene required for cancer cell survival
2020· 2 citedOpen Access
U2AF1(S34F) Mutant Hematopoietic Cells Require Expression of Wild-Type U2af1 for Survival
Blood·2018
Abstract 5112: <i>U2af1</i>, a spliceosome gene commonly mutated in MDS, is required for hematopoiesis
Cancer Research·2018
Corticotropin‐releasing factor receptor type 2‐deficient mice display impaired coping behaviors during stress
Genes Brain & Behavior·2005· 32 cited
Small interfering RNA production by enzymatic engineering of DNA (SPEED)
Proceedings of the National Academy of Sciences·2004· 110 citedOpen Access
Molecular Study of Interactions between Hematopoietic Stem Cells and Stromal Cells
DSpace@MIT (Massachusetts Institute of Technology)·2002Open Access
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Frequent Co-authors

Jack H. Landmann(8), Mehmet Emrah Selli(8), John M. Warrington(7), Jufang Chang(7), Yu-Sung Hsu(6), Nathan Singh(6), John Lattin(5), Helen Ha(5), Tien-Ching Chang(5), Brian A. Wadugu(4), Matthew Ndonwi(4), Joseph Bradley(4), Matthew J. Walter(4), Harmony Saunders(4), Lauryn R. Werner(4), Christy R. Hagan(4), Mary P. Stenzel‐Poore(3), Natalie L. Kingston(3), Graham D. Hogg(3), Mark P. Foster(3)