Akira Shigenaga

Fukuyama University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index2.2kcitations142works1.02yr avg
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Research Topics

Chemical Synthesis and Analysis(80), Click Chemistry and Applications(36), Synthesis and Catalytic Reactions(13), Carbohydrate Chemistry and Synthesis(12), Cyclization and Aryne Chemistry(11)

Publications142 total

Theoretical Study of the Substituent Effect on the Diradical Character of <i>α</i>-Substituted <i>α</i>,3-Didehydrotoluenes
Chemical and Pharmaceutical Bulletin·2025Open Access
Tyrosine bioconjugation using stably preparable urazole radicals
Tetrahedron Chem·2024· 2 citedOpen Access
Theoretical study to gain fundamental insight into reaction mechanism of N–S acyl transfer of <i>N</i>‐sulfanylethylanilide‐based protein labeling reagent on protein surface
Journal of Peptide Science·2023
Cover Feature: Residue‐Selective C−H Sulfenylation Enabled by Acid‐Activated <i>S</i>‐Acetamidomethyl Cysteine Sulfoxide with Application to One‐Pot Stapling and Lipidation Sequence (Chem. Eur. J. 26/2023)
Chemistry - A European Journal·2023· 1 citedOpen Access
Residue‐Selective C−H Sulfenylation Enabled by Acid‐Activated <i>S</i>‐Acetamidomethyl Cysteine Sulfoxide with Application to One‐Pot Stapling and Lipidation Sequence
Chemistry - A European Journal·2023· 12 cited
Development of a novel tocopheryl ester for suppression of lipid accumulation without cytotoxicity by optimization of dicarboxylic ester moiety
Biochemistry and Biophysics Reports·2022· 3 citedOpen Access
Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells
Cell chemical biology·2022· 9 cited
Late-stage macrolactonisation enabled by tandem acyl transfers followed by desulphurisation
Chemical Communications·2022· 2 cited
Identification of Functional Domains of CXCL14 Involved in High-Affinity Binding and Intracellular Transport of CpG DNA
The Journal of Immunology·2021· 8 citedOpen Access
Sequence-Independent Traceless Method for Preparation of Peptide/Protein Thioesters Using CPaseY-Mediated Hydrazinolysis
Chemical and Pharmaceutical Bulletin·2020· 5 citedOpen Access
Sulfanylmethyldimethylaminopyridine as a Useful Thiol Additive for Ligation Chemistry in Peptide/Protein Synthesis
Organic Letters·2020· 16 cited
Development of a Turn-On Fluorescent Traceable Linker Employing &lt;i&gt;N&lt;/i&gt;-Sulfanylethylcoumarinyl Amide for the Enrichment and Visualization of Target Proteins
Chemical and Pharmaceutical Bulletin·2020· 2 citedOpen Access
Deprotection of <i>S</i>-acetamidomethyl cysteine with copper(<scp>ii</scp>) and 1,2-aminothiols under aerobic conditions
Organic & Biomolecular Chemistry·2020· 14 cited
Theoretical study on reaction mechanism of phosphate-catalysed N–S acyl transfer of <i>N</i>-sulfanylethylanilide (SEAlide)
Organic & Biomolecular Chemistry·2020· 11 cited
Development of Chemical Biology Tools Focusing on Peptide/Amide Bond Cleavage Reaction
Chemical and Pharmaceutical Bulletin·2019· 6 citedOpen Access
Copper-Mediated Deprotection of Thiazolidine and Selenazolidine Derivatives Applied to Native Chemical Ligation
The Journal of Organic Chemistry·2019· 26 cited
Asymmetric Synthesis of α‐Amino Phosphonic Acids using Stable Imino Phosphonate as a Universal Precursor
Chemistry - A European Journal·2019· 22 cited
A Photo-Activatable Peptide Mimicking Functions of Apolipoprotein A-I
Biological and Pharmaceutical Bulletin·2019· 8 citedOpen Access
Looking Back on Study Abroad at The Scripps Research Institute
YAKUGAKU ZASSHI·2019Open Access
Traceless synthesis of protein thioesters using enzyme-mediated hydrazinolysis and subsequent self-editing of the cysteinyl prolyl sequence
Chemical Communications·2019· 16 cited
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Frequent Co-authors

Akira Otaka(41), Kohei Sato(14), Kohei Tsuji(11), Tsubasa Inokuma(11), Kohji Itoh(6), Hiroyuki Saito(6), Jun Yamamoto(6), Keisuke Aihara(6), Shugo Tsuda(5), Naoto Naruse(5), Akira Otaka(5), Ken Sakamoto(4), Daisuke Tsuji(4), Yoshitake Sumikawa(4), Kosuke Tanegashima(4), Takahiko Hara(4), Ichirō Suzuki(4), Hisao Nemoto(4), Masayuki Shibuya(4), Masaya Denda(4)