Rosamaria Orlando

Istituto Neurologico Mediterraneo — Italy

Neuroscience · Life Sciences

13h-index702citations28works1.52yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(14), Receptor Mechanisms and Signaling(4), Immune Response and Inflammation(3), Memory and Neural Mechanisms(3), Ion channel regulation and function(3)

Publications28 total

Preclinical and clinical study on type 3 metabotropic glutamate receptors in Parkinson’s disease
npj Parkinson s Disease·2025· 2 citedOpen Access
Metabotropic Glutamate Receptors Type 3 and 5 Feature the“NeuroTransmitter-type” of Glioblastoma: A Bioinformatic Approach
Current Neuropharmacology·2024· 1 citedOpen Access
Blunted type-5 metabotropic glutamate receptor-mediated polyphosphoinositide hydrolysis in two mouse models of monogenic autism
Neuropharmacology·2023· 5 cited
GPCR interactions involving metabotropic glutamate receptors and their relevance to the pathophysiology and treatment of CNS disorders
Neuropharmacology·2023· 34 cited
Synergic action of L-acetylcarnitine and L-methylfolate in Mouse Models of Stress-Related Disorders and Human iPSC-Derived Dopaminergic Neurons
Frontiers in Pharmacology·2022· 3 citedOpen Access
Changes in mGlu5 Receptor Signaling Are Associated with Associative Learning and Memory Extinction in Mice
Life·2022· 4 citedOpen Access
The bacterial quorum sensing molecule, 2-heptyl-3-hydroxy-4-quinolone (PQS), inhibits signal transduction mechanisms in brain tissue and is behaviorally active in mice
Pharmacological Research·2021· 7 cited
mGlu3 receptor regulates microglial cell reactivity in neonatal rats
Journal of Neuroinflammation·2021· 27 citedOpen Access
Additional file 6 of mGlu3 receptor regulates microglial cell reactivity in neonatal rats
Figshare·2021Open Access
mGlu3 receptor regulates microglial cell reactivity in neonatal rats
2020· 1 citedOpen Access
Targeting mGlu Receptors for Optimization of Antipsychotic Activity and Disease-Modifying Effect in Schizophrenia
Frontiers in Psychiatry·2019· 43 citedOpen Access
In Vivo Non-radioactive Assessment of mGlu5 Receptor-Activated Polyphosphoinositide Hydrolysis in Response to Systemic Administration of a Positive Allosteric Modulator
Frontiers in Pharmacology·2018· 13 citedOpen Access
Stress as risk factor for Alzheimer’s disease
Pharmacological Research·2018· 99 cited
Targeting mGlu5 Metabotropic Glutamate Receptors in the Treatment of Cognitive Dysfunction in a Mouse Model of Phenylketonuria
Frontiers in Neuroscience·2018· 15 citedOpen Access
Targeting metabotropic glutamate receptors in the treatment of primary brain tumors
Current Opinion in Pharmacology·2018· 8 cited
Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system
Neuropharmacology·2017· 100 citedOpen Access
Paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus
Pharmacological Research·2016· 9 cited
Type-7 metabotropic glutamate receptors negatively regulate α1-adrenergic receptor signalling
Neuropharmacology·2016· 5 cited
Antidepressant activity of fingolimod in mice
Pharmacology Research & Perspectives·2015· 55 citedOpen Access
Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 receptor agonists, LY379268 and LY354740
Neuropharmacology·2014· 10 cited
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Frequent Co-authors

Ferdinando Nicoletti(23), Giuseppe Battaglia(14), Luisa Iacovelli(12), Luisa Di Menna(10), Valeria Bruno(10), Francesco Matrisciano(6), Alessandra Caruso(5), Sergio Scaccianoce(5), Anna Rita Zuena(5), Jérôme Mairesse(4), Filippo Caraci(4), Gemma Molinaro(4), Marta Motolese(4), Daniela Melchiorri(4), Luigi di Nuzzo(4), Francesco Fazio(4), Julien Pansiot(4), Olivier Baud(4), Roxana Paula Ginerete(4), Marika Alborghetti(4)