Vsevolod Katritch

QB3 — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

77h-index28.6kcitations250works3.72yr avg
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Research Topics

Receptor Mechanisms and Signaling(136), Neuropeptides and Animal Physiology(92), Pharmacological Receptor Mechanisms and Effects(37), Computational Drug Discovery Methods(22), Chemical Synthesis and Analysis(20)

Publications250 total

Development of potent, selective cPLA2 inhibitors for targeting neuroinflammation in Alzheimer’s disease and other neurodegenerative disorders
npj Drug Discovery.·2026· 1 citedOpen Access
Differential Effects of Sodium on Agonist-Induced Conformational Transitions and Signaling at μ and κ Opioid Receptors
Biochemistry·2025· 1 cited
Navigating structure-based drug discovery with emerging innovations in physics- and knowledge-based approaches
npj Drug Discovery.·2025· 1 citedOpen Access
Structure-guided design of a peripherally restricted chemogenetic system
UNC Libraries·2025Open Access
V-synthes2 - the Next Generation Tool for Structure-based Virtual Screening of Giga-scale Chemical Spaces
2025· 1 citedOpen Access
Structural insights into the mechanism of activation and inhibition of the prostaglandin D2 receptor 1
Nature Communications·2025· 1 citedOpen Access
Structure-guided design of partial agonists at an opioid receptor
UNC Libraries·2025Open Access
Exceptionally Potent Chiral Anandamide Analogs
Journal of Medicinal Chemistry·2025· 1 citedOpen Access
Differential effects of sodium on agonist-induced conformational transitions and signaling at μ and κ opioid receptors
2025Open Access
Cryo-EM structure of the prostaglandin D2 receptor 1 (DP1) complex in inactive and active states
EMPIAR dataset·2025Open Access
Novel Tetraolefinic Chain Phenyl Substituted Endocannabinoid Probes
Journal of Medicinal Chemistry·2025· 1 citedOpen Access
Synthesis and Pharmacology of a Morphinan-Derived Dual Mu–Kappa Opioid Receptor Agonist Analgesic
ACS Chemical Neuroscience·2025· 2 cited
ANGIOTENSIN-(1-5) IS A BIOLOGICALLY ACTIVE HORMONE OF THE RENIN-ANGIOTENSIN SYSTEM AND A POTENT AT2-RECEPTOR AGONIST
Journal of Hypertension·2025
A Photochromic Controller for Reversible Regulation of Peripheral Opioid Analgesia
Journal of Pain·2025
Structure-guided design of partial agonists at an opioid receptor
Nature Communications·2025· 7 citedOpen Access
Development of Potent, Selective cPLA2 Inhibitors for Targeting Neuroinflammation in Alzheimer’s Disease and Other Neurodegenerative Disorders
2025· 4 citedOpen Access
Modulation of Kappa Opioid Receptor Functional Selectivity, Efficacy and Subtype Selectivity (Abstract ID: 156788)
Journal of Pharmacology and Experimental Therapeutics·2025
An opioid efficacy switch for reversible optical control of peripheral analgesia
2024· 2 citedOpen Access
Structural insights into the high basal activity and inverse agonism of the orphan receptor GPR6 implicated in Parkinson’s disease
Science Signaling·2024· 13 citedOpen Access
Structure-guided design of a peripherally restricted chemogenetic system
Cell·2024· 8 citedOpen Access
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Frequent Co-authors

Raymond C. Stevens(44), Vadim Cherezov(35), Gye Won Han(28), Bryan L. Roth(14), Xi‐Ping Huang(12), Wei Liu(10), Daniel Wacker(9), Cornelius Gati(8), Uwe Weierstall(8), Huixian Wu(7), Thomas A. White(7), Gustavo Fenalti(6), Ruben Abagyan(6), Eyal Vardy(6), Andrii Ishchenko(6), Nadia A. Zatsepin(6), Chong Wang(6), John D. McCorvy(6), Nilkanth Patel(6), Aaron A. Thompson(5)