F. Gasparini

Novartis (Switzerland) — Switzerland

Physics and Astronomy · Physical Sciences

96h-index45.5kcitations775works3.62yr avg
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Research Topics

Particle physics theoretical and experimental studies(547), High-Energy Particle Collisions Research(450), Quantum Chromodynamics and Particle Interactions(283), Particle Detector Development and Performance(120), Neuroscience and Neuropharmacology Research(79)

Publications208 total

Multiparametric MRI assessment of acute neuroinflammation in a murine model of peripheral LPS stimulation
BMC Medical Imaging·2025Open Access
VHB937, a TREM2 Stabilizing and Activating Antibody Strongly Reduces Pathology After Peripheral Administration in a Broad Range of Animal Models for Neuroinflammation and Neurodegeneration (P4-4.004)
Neurology·2024· 5 cited
Activated Microglia by Cleavage-Reduced Trem2 Diminish Plaque Load in App23 Mice
SSRN Electronic Journal·2024Open Access
Central and Peripheral Inflammation in Mild Cognitive Impairment in the Context of Alzheimer’s Disease
International Journal of Molecular Sciences·2023· 20 citedOpen Access
P407 MULTIDIMENSIONAL ASSESSMENT OF THE ELDERLY PATIENT WITH SEVERE AORTIC STENOSIS: THE ROLE OF FRAILTY IN THE CHOICE OF TREATMENT (TAVI/SAVR)
European Heart Journal Supplements·2023Open Access
Genetic models of cleavage-reduced and soluble TREM2 reveal distinct effects on myelination and microglia function in the cuprizone model
Journal of Neuroinflammation·2023· 14 citedOpen Access
The Analytical Method algorithm for trigger primitives generation at the LHC Drift Tubes detector
Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment·2023· 12 citedOpen Access
Soluble TREM2 induces microglia dysfunction and brain damage while cleavage-reduced TREM2 shows sustained microglia activation with enhanced myelination in the cuprizone model
Research Square (Research Square)·2022Open Access
Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease
Cell Reports·2022· 77 citedOpen Access
Soluble TREM2 induces microglia dysfunction and brain damage while cleavage-reduced TREM2 shows sustained microglia activation with enhanced remyelination in the cuprizone model
Research Square (Research Square)·2022Open Access
Sustained TREM2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease
2021· 2 citedOpen Access
Regional brain mGlu5 receptor occupancy following single oral doses of mavoglurant as measured by [11C]-ABP688 PET imaging in healthy volunteers
NeuroImage·2021· 9 citedOpen Access
Irradiation aging of the CMS Drift Tube muon detector
Radiation Physics and Chemistry·2020· 1 citedOpen Access
Study of the effects of radiation on the CMS Drift Tubes Muon Detector for the HL-LHC
Journal of Instrumentation·2019· 4 citedOpen Access
Study of the Effects of Radiation at the CERN Gamma Irradiation Facility on the CMS Drift Tube Muon Detector for HL-LHC
2019Open Access
Inhibiting mGluR5 activity by AFQ056/Mavoglurant rescues circuit-specific functional connectivity in Fmr1 knockout mice
NeuroImage·2019· 26 citedOpen Access
Protein synthesis levels are increased in a subset of individuals with fragile X syndrome
Human Molecular Genetics·2018· 22 citedOpen Access
The network of photodetectors and diode lasers of the CMS Link alignment system
Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment·2018· 1 citedOpen Access
Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome
University of Southern Denmark Research Portal (University of Southern Denmark)·2018Open Access
Protein synthesis levels are increased in a subset of individuals with fragile X syndrome
Human Molecular Genetics·2018· 70 citedOpen Access
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Frequent Co-authors

Baltazar Gomez‐Mancilla(12), Peter J. Flor(11), Rainer Kühn(10), Will Spooren(9), Ivo Vranesic(8), Ralf Kühn(7), Natacha Stoehr(5), Donald R. Johns(5), Valeria Bruno(5), Giuseppe Battaglia(5), Ferdinando Nicoletti(5), Thérèse Di Paolo(5), Athina Markou(4), Andreea Pop(4), Rob Willemsen(4), Kurt Lingenhöhl(3), Micheline Heinrich(3), Stephan Urwyler(3), Mark A. Varney(3), Edwin C. Johnson(3)