Lianwan Chen

Chinese Academy of Sciences — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index843citations32works4.22yr avg
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Research Topics

Genetics, Aging, and Longevity in Model Organisms(14), Mitochondrial Function and Pathology(7), Photosynthetic Processes and Mechanisms(6), Reproductive Biology and Fertility(3), Selenium in Biological Systems(3)

Publications32 total

Structural insights into distinct filamentation states reveal a regulatory mechanism for bacterial STING activation
mBio·2025Open Access
In situ structure of the mouse sperm central apparatus reveals mechanistic insights into asthenozoospermia
Cell Research·2025· 10 citedOpen Access
Surface lipoprotein sorting by crosstalk between Lpt and Lol pathways in gram-negative bacteria
Nature Communications·2025· 8 citedOpen Access
Genetically encoded horse heart myoglobin for electron microscopy imaging in mammalian cells
Chemical Engineering Journal·2025
SMNK-1 and VHA-18 are essential for FB-MO complex assembly and transport during spermatogenesis in C. elegans
2025Open Access
Mitochondrial defects triggered by <i>amg-1</i> mutation elicit UPRmt and phagocytic clearance during spermatogenesis in <i>C. elegans</i>
Development·2024· 7 citedOpen Access
Protocol for CRISPR-Cas9-mediated genome editing to study spermatogenesis in Caenorhabditis elegans
STAR Protocols·2023· 4 citedOpen Access
RNA-binding protein complex AMG-1/SLRP-1 mediates germline development and spermatogenesis by maintaining mitochondrial homeostasis in Caenorhabditis elegans
Science Bulletin·2023· 7 cited
The mechanism of STING autoinhibition and activation
Molecular Cell·2023· 71 cited
Lipoprotein sorting to the cell surface via a crosstalk between the Lpt and Lol pathways during outer membrane biogenesis
2022· 1 citedOpen Access
mtRBP complex AMG-1/SLRP-1 mediates germline development and spermatogenesis by maintaining mitochondrial homeostasis in Caenorhabditis elegans
Research Square (Research Square)·2022Open Access
MIG-23 is involved in sperm migration by modulating extracellular ATP levels in <i>Ascaris suum</i>
Development·2022· 1 citedOpen Access
Application of auxin-induced protein degradation technique in&amp;lt;italic&amp;gt;Caenorhabditis&amp;lt;/italic&amp;gt;&amp;lt;italic&amp;gt; elegans&amp;lt;/italic&amp;gt; spermatogenesis
Scientia Sinica Vitae·2022
The homolog of human ecto-nucleoside triphosphate diphosphohydrolase MIG-23 is involved in sperm migration by modulating extracellular ATP levels in <i>Ascaris suum</i>
2021Open Access
Membrane contact site-dependent cholesterol transport regulates Na+/K+-ATPase polarization and spermiogenesis in Caenorhabditis elegans
Developmental Cell·2021· 16 citedOpen Access
Mitochondrial RBP Complex AMG-1/SLRP-1 is Required for Germline Development and Reproductive Success in &lt;i&gt;Caenorhabditis elegans&lt;/i&gt;
SSRN Electronic Journal·2021Open Access
Polarization of Na &lt;sup&gt;+&lt;/sup&gt;/K &lt;sup&gt;+&lt;/sup&gt;-Atpase Dependent on Cholesterol Transport Through Membrane Contact Sites Regulates Spermiogenesis and Reproductive Success in &lt;i&gt;C. Elegans&lt;/i&gt;
SSRN Electronic Journal·2020Open Access
Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors
Journal of Neuroscience·2019· 76 citedOpen Access
The glial actin cytoskeleton regulates neuronal ciliogenesis
Cell Research·2016· 6 citedOpen Access
The lysosomal membrane protein SCAV-3 maintains lysosome integrity and adult longevity
The Journal of Cell Biology·2016· 102 citedOpen Access
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Frequent Co-authors

Long Miao(16), Shan Jin(6), Long Miao(6), Xia Wang(5), Ning Wang(5), Chonglin Yang(4), Qiushi Wang(4), Zheng Cao(4), Baochen Du(4), Zhiheng Yuan(4), Peng Wang(4), Ruijun He(4), Yanmei Zhao(4), Xiaojing Ma(4), Xinyan Chen(4), Qi Zhang(4), Yanmei Zhao(4), Youli Jian(3), Xuezhao Liu(3), Yingchun Wang(3)