Alexis Cuffel

Inserm — France

Medicine · Health Sciences

8h-index576citations22works3.02yr avg
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Research Topics

CAR-T cell therapy research(18), Viral Infectious Diseases and Gene Expression in Insects(5), Lymphoma Diagnosis and Treatment(3), Virus-based gene therapy research(3), Acute Lymphoblastic Leukemia research(3)

Publications22 total

Characteristics and outcome determinants in children, adolescents and young adults who failed tisagenlecleucel for B-cell acute lymphoblastic leukemia
Leukemia·2026
Preclinical evidence of anti-CD19 CAR-T cell in vitro and in vivo efficacy against CD19-expressing acute myeloid leukemia
Current Research in Translational Medicine·2026
Routine Monitoring of CAR‐T‐Cells Expansion and Persistence in Patients With Aggressive Large B‐Cell Lymphoma by Flow Cytometry: A Single‐Center Experience
Hematological Oncology·2025· 2 citedOpen Access
Identification of the conditions and minimum requirements necessary for the release of autologous fresh CAR T-cell products under hospital exemption: a position paper from the WP-bioproduction of the UNITC consortium
Bone Marrow Transplantation·2025· 4 cited
Characteristics and Outcome Determinants in Children, Adolescents and Young Adults Who Failed Tisagenlecleucel for B-Cell Acute Lymphoblastic Leukemia
Blood·2024Open Access
Anti-CD19 CAR-T Cells for CD19+acute Myeloid Leukemia: A Preclinical Study
Blood·2024
Neurofilament light chain levels as an early predictive biomarker of neurotoxicity after CAR T-cell therapy
Journal for ImmunoTherapy of Cancer·2024· 14 citedOpen Access
Brexucabtagene autoleucel in relapsed or refractory mantle cell lymphoma, intention-to-treat use in the DESCAR-T registry
Haematologica·2024· 7 citedOpen Access
Success of donor‐derived <scp>CAR</scp>‐T cells after failure of autologous <scp>CD19 CAR‐T</scp> cells (tisagenlecleucel) in B‐cell acute lymphoblastic leukaemia
British Journal of Haematology·2024· 5 cited
Early lymphocyte reconstitution and viral infections in adolescents and adults transplanted for sickle cell disease
Bone Marrow Transplantation·2024
Germline HLA-DQ genotype influences response to CAR T-cell therapy in patients with large B-cell lymphoma
2024· 1 citedOpen Access
Development of optimized cytotoxicity assays for assessing the antitumor potential of CAR-T cells
Journal of Immunological Methods·2023· 5 cited
Low Disease Burden Pre-CAR-T Cell Therapy for Children and AYA with B-ALL Is Associated with an Impaired Outcome When Obtained through Intensification of the Bridging Therapy
Blood·2023· 2 cited
A major role for CD4+ T cells in driving cytokine release syndrome during CAR T cell therapy
Cell Reports Medicine·2023· 49 citedOpen Access
Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4+ CAR T-cell antitumor activity
Nature Cancer·2023· 118 citedOpen Access
Humoral and cellular responses to SARS-CoV-2 BNT162b2 vaccination in allogeneic hematopoietic stem cell transplantation recipients
Vaccine·2022· 6 citedOpen Access
Real-world characteristics of T-cell apheresis and clinical response to tisagenlecleucel in B-cell lymphoma
Blood Advances·2022· 29 citedOpen Access
Lenalidomide Exposure at Time of CAR T-Cells Expansion Enhances Response of Refractory/Relapsed Aggressive Large B-Cell Lymphomas
Blood·2021· 12 cited
Kte-X19 in Relapsed or Refractory Mantle-Cell Lymphoma, a "Real-Life" Study from the Descar-T Registry and Lysa Group
Blood·2021· 16 cited
Suivi immunologique des patients traités par cellules CAR-T pour hémopathie maligne: recommandations du groupe CARTi et de la Société francophone de greffe de moelle et de thérapie cellulaire (SFGM-TC)
Bulletin du Cancer·2021· 8 citedOpen Access
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Frequent Co-authors

Sophie Caillat‐Zucman(15), Roberta Di Blasi(6), Florence Morin(5), Catherine Thiéblemont(5), Vincent Allain(5), Jérôme Larghero(5), Jean‐Hugues Dalle(5), Isabelle Madelaine(4), Nathalie Parquet(4), Anne Brignier(4), Jean‐Baptiste Latouche(4), Misa Eugène Norbert(4), Camille Giverne(4), Olivier Boyer(4), J. Martinet(4), Karima Yakouben(4), Delphine Chaillou(4), Élodie Lainey(4), Chloé Arfeuille(4), Florian Chevillon(4)