Vania Lo Presti

Children's Hospital of Philadelphia — United States

Medicine · Health Sciences

8h-index275citations24works3.02yr avg
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Research Topics

CAR-T cell therapy research(9), Erythrocyte Function and Pathophysiology(9), Hemoglobinopathies and Related Disorders(8), Virus-based gene therapy research(7), CRISPR and Genetic Engineering(4)

Publications24 total

TNFα signaling restores steady-state hematopoiesis in a TNFαKO mouse model of anemia of inflammation
Blood·2025· 1 citedOpen Access
Engineering anti-BCMA CAR T cells for enhancing myeloma killing efficacy via apoptosis regulation
Nature Communications·2025· 8 citedOpen Access
TNFα Plays Essential Role in Resolution of Anemia of Inflammation in Tnfαko Mice Treated with Heat-Killed <i>Brucella Abortus</i>
Blood·2024Open Access
Combining CRISPR-Cas9 and TCR exchange to generate a safe and efficient cord blood-derived T cell product for pediatric relapsed AML
Journal for ImmunoTherapy of Cancer·2024· 5 citedOpen Access
Engineering BCMA CAR T cells for myeloma-targeted cargo delivery
2024· 1 cited
Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch
Journal for ImmunoTherapy of Cancer·2022· 34 citedOpen Access
TNFα and Anti-IFNγ Rescues Chronic Anemia of Inflammation Phenotype in Tnfαko Mice Treated with Heat-Killed <i>Brucella Abortus</i>
Blood·2022
Gene Editing of Checkpoint Molecules in Cord Blood-Derived Dendritic Cells and CD8 <sup>+</sup> T Cells Using CRISPR-Cas9
The CRISPR Journal·2022· 1 cited
ARCOBALENO cell therapy to treat pediatric cancer patients
2022Open Access
TNFα Controls the Delicate Balance between Erythropoiesis and Stem Cell Exhaustion during Inflammatory Stress
Blood·2021
Efficient lentiviral transduction method to gene modify cord blood CD8+ T cells for cancer therapy applications
Molecular Therapy — Methods & Clinical Development·2021· 33 citedOpen Access
Gene Augmentation and Editing to Improve TCR Engineered T Cell Therapy against Solid Tumors
Vaccines·2020· 14 citedOpen Access
Clinical Grade Production of Wilms’ Tumor-1 Loaded Cord Blood-Derived Dendritic Cells to Prevent Relapse in Pediatric AML After Cord Blood Transplantation
Frontiers in Immunology·2020· 14 citedOpen Access
Correcting β-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity
Blood·2020· 40 citedOpen Access
Lack of Gdf11 does not improve anemia or prevent the activity of RAP-536 in a mouse model of β-thalassemia
Blood·2019· 63 citedOpen Access
Correcting Non-Transfusion Dependent β-Thalassemia by Utilizing a Combined Therapy that Modulates EPO Activity by Limiting Erythroid Cellular Iron Intake
Blood·2018
Lack of GDF11 Does Not Ameliorate Erythropoiesis in β-Thalassemia and Does Not Prevent the Activity of the Trap-Ligand RAP-536
Blood·2018· 1 cited
Use of cord blood derived T-cells in cancer immunotherapy: milestones achieved and future perspectives
Expert Review of Hematology·2018· 13 cited
Absence of Interleukin-6 Protects Murine Bone Marrow Erythropoiesis Under Inflammation, in a Process Reversible By Iron Mediated Reactive Oxygen Species Upregulation
Blood·2017
Short-term administration of JAK2 inhibitors reduces splenomegaly in mouse models of β-thalassemia intermedia and major
Haematologica·2017· 33 citedOpen Access
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Frequent Co-authors

Stefano Rivella(14), Carla Casu(13), Stefan Nierkens(9), Amaliris Guerra(6), Ritama Gupta(6), Ester Dünnebach(5), Paraskevi Rea Oikonomidou(4), Mariam Aghajan(4), Emir O’Hara(4), Shuling Guo(4), Annelisa M. Cornel(4), Maud Plantinga(4), Jürgen Kuball(4), Niek P. van Til(4), Carlo Castruccio Castracani(4), Raffaella Gozzelino(4), Laura Bennett(4), Robert F. Paulson(4), Peter Kurre(4), Laura Breda(3)