Jason Waithman

The University of Western Australia — Australia

Immunology and Microbiology · Life Sciences

27h-index5.6kcitations80works8.92yr avg
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Research Topics

Immunotherapy and Immune Responses(44), Immune Cell Function and Interaction(28), T-cell and B-cell Immunology(25), CAR-T cell therapy research(25), Cancer Immunotherapy and Biomarkers(24)

Publications80 total

Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8+ T cells in lymph nodes
Nature Immunology·2026
Antigen reactivity defines tissue-resident memory and exhausted T cells in tumors
Nature Immunology·2025· 4 citedOpen Access
Comparative analysis of malignant pleural effusion and peripheral blood reveals unique T cell signatures associated with survival in mesothelioma patients
Oxford Open Immunology·2025Open Access
Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanoma
Immunity·2025· 6 cited
Antigen reactivity defines tissue-resident memory and exhausted T cells in tumours
2025· 2 citedOpen Access
Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
Nature Communications·2025· 6 citedOpen Access
Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery
Nature·2025· 31 citedOpen Access
Interleukin-4 modulates type I interferon to augment antitumor immunity
Science Advances·2025· 4 citedOpen Access
CRISPR engineering of armored CAR T cells enables tumor restricted payload delivery with enhanced efficacy and safety
2025Open Access
Transcriptional rewiring in CD8+ T cells: implications for CAR-T cell therapy against solid tumours
Frontiers in Immunology·2024· 4 citedOpen Access
Decipher: A computational pipeline to extract context-specific mechanistic insights from single-cell profiles
2024Open Access
Tumor-site directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
2024Open Access
CD4 <sup>+</sup> T cell immunity against cutaneous melanoma encompasses multifaceted MHC II–dependent responses
Science Immunology·2024· 59 cited
Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years
Frontiers in Immunology·2023· 5 citedOpen Access
Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years
2023
Type I interferon subtypes differentially activate the anti-leukaemic function of natural killer cells
Frontiers in Immunology·2022· 15 citedOpen Access
Tissue-resident memory T cells in the era of (Neo) adjuvant melanoma management
Frontiers in Immunology·2022· 17 citedOpen Access
Non-severe burn injury increases cancer incidence in mice and has long-term impacts on the activation and function of T cells
Burns & Trauma·2022· 5 citedOpen Access
Targeting Cross-Presentation as a Route to Improve the Efficiency of Peptide-Based Cancer Vaccines
Cancers·2021· 16 citedOpen Access
Directing the Future Breakthroughs in Immunotherapy: The Importance of a Holistic Approach to the Tumour Microenvironment
Cancers·2021· 4 citedOpen Access
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Frequent Co-authors

Ben Wylie(10), Bree Foley(10), William R. Heath(9), Teagan Wagner(9), Thomas Gebhardt(9), Anthony Buzzai(8), Sammy Bedoui(7), Vanessa S. Fear(7), Ken Shortman(6), Federico Carbone(6), Katherine M. Audsley(6), Alison M. McDonnell(6), Katharina Hochheiser(5), Paul A. Beavis(5), Weisan Chen(5), Justine D. Mintern(5), Jesse Armitage(5), Hannah V. Newnes(5), Samantha Barnes(5), Mark N. Cruickshank(5)