Erhard Bieberich

University of Kentucky — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

49h-index7.4kcitations161works5.52yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Sphingolipid Metabolism and Signaling(80), Lipid Membrane Structure and Behavior(36), Glycosylation and Glycoproteins Research(23), Extracellular vesicles in disease(16), Carbohydrate Chemistry and Synthesis(16)

Publications161 total

Ceramide Links Alzheimer’s Disease to Decreased Cancer Risk: A Lipid Behind the Enigma of Inverse Comorbidity
Cancer Research·2025· 1 cited
Targeting ABCD1-ACOX1-MET/IGF1R axis suppresses multiple myeloma
Leukemia·2025· 2 citedOpen Access
Staying sane in the membrane: Neutral sphingomyelinase 2 as a master regulator of plasma membrane ceramide
Journal of Lipid Research·2024· 6 citedOpen Access
Transcriptomics analysis reveals potential regulatory role of <scp>nSMase2</scp> (<i>Smpd3</i>) in nervous system development and function of middle‐aged mouse brains
Genes Brain & Behavior·2024· 3 citedOpen Access
Ceramide‐mediated orchestration of oxidative stress response through filopodia‐derived small extracellular vesicles
Journal of Extracellular Vesicles·2024· 14 citedOpen Access
Abnormal Regulation of Mitochondrial Sphingolipids during Aging and Alzheimer’s Disease
ASN NEURO·2024· 7 citedOpen Access
Chronic nSMase2 Inhibition Suppresses Neuronal Exosome Spreading In Vivo &amp; Induces Sex‐Specific Attenuation of AD Pathology in APP<sup>NL‐F/NL‐F</sup> Knock‐In Mice
Alzheimer s & Dementia·2023Open Access
Regulated translocation of neutral sphingomyelinase-2 to the plasma membrane drives insulin resistance in steatotic hepatocytes
Journal of Lipid Research·2023· 12 citedOpen Access
Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer’s disease pathology in the 5xFAD mouse
Acta Neuropathologica Communications·2023· 23 citedOpen Access
The S1P receptor 1 antagonist Ponesimod reduces TLR4-induced neuroinflammation and increases Aβ clearance in 5XFAD mice
EBioMedicine·2023· 32 citedOpen Access
Chronic nSMase inhibition suppresses neuronal exosome spreading and sex-specifically attenuates amyloid pathology in APP knock-in Alzheimer's disease mice
Neurobiology of Disease·2023· 20 citedOpen Access
Novel Isolation Method Reveals Sex-Specific Composition and Neurotoxicity of Small Extracellular Vesicles in a Mouse Model of Alzheimer’s Disease
Cells·2023· 9 citedOpen Access
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection
Nature Communications·2023· 47 citedOpen Access
In Memoriam, Dr. Robert K. Yu
ASN NEURO·2023Open Access
Synthesis, Processing, and Function of N-Glycans in N-Glycoproteins
Advances in neurobiology·2022· 14 cited
Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking
Proceedings of the National Academy of Sciences·2022· 18 citedOpen Access
FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer’s disease expressing APOE4
Biomedicine & Pharmacotherapy·2022· 19 citedOpen Access
Function of ceramide transfer protein for biogenesis and sphingolipid composition of extracellular vesicles
Journal of Extracellular Vesicles·2022· 75 citedOpen Access
Neutral Sphingomyelinase 2 Mediates Oxidative Stress Effects on Astrocyte Senescence and Synaptic Plasticity Transcripts
Molecular Neurobiology·2022· 15 citedOpen Access
Inhibition of ceramide accumulation in AdipoR1–/– mice increases photoreceptor survival and improves vision
JCI Insight·2022· 42 citedOpen Access
page 1 of 9Next →

Frequent Co-authors

Guanghu Wang(20), Michael B. Dinkins(12), Somsankar Dasgupta(9), Jeane Silva(7), Kannan Krishnamurthy(7), Gu Zhu(6), Qian He(6), Robert K. Yu(5), Ahmed Elsherbini(4), Stefka D. Spassieva(4), Brian G. Condie(3), Sarah MacKinnon(3), Simone M. Crivelli(3), Ji Na Kong(3), Ernst Bause(3), Zhihui Zhu(3), Inas Helwa(2), Yutao Liu(2), Ji‐Na Kong(2), Leesa Bryant(2)