Lakshmanan Jagannathan

Medicine · Health Sciences

12h-index717citations23works1.02yr avg
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Research Topics

Tuberculosis Research and Epidemiology(3), Epigenetics and DNA Methylation(3), Genetics and Neurodevelopmental Disorders(3), MicroRNA in disease regulation(2), Computational Drug Discovery Methods(2)

Publications23 total

P678: Role of de novo variants in genetic disorders with new insights and clinical implications
Genetics in Medicine Open·2025Open Access
Focused Exome Sequencing Gives a High Diagnostic Yield in the Indian Subcontinent
Journal of Molecular Diagnostics·2024· 2 citedOpen Access
DrugMechDB: A Curated Database of Drug Mechanisms
Scientific Data·2023· 14 citedOpen Access
DrugMechDB: A Curated Database of Drug Mechanisms
2023· 5 citedOpen Access
Pompe disease ascertained through The Lantern Project, 2018–2021: Next-generation sequencing and enzymatic testing to overcome obstacles to diagnosis
Molecular Genetics and Metabolism·2023· 9 cited
Beyond the single average tumor: Understanding IO combinations using a clinical QSP model that incorporates heterogeneity in patient response
CPT Pharmacometrics & Systems Pharmacology·2021· 20 citedOpen Access
A single NGS‐based assay covering the entire genomic sequence of the <i>DMD</i> gene facilitates diagnostic and newborn screening confirmatory testing
Human Mutation·2021· 51 cited
Cadmium exposure upregulates SNAIL through miR-30 repression in human lung epithelial cells
Toxicology and Applied Pharmacology·2019· 38 citedOpen Access
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1
Molecular Carcinogenesis·2018· 60 cited
Systems Biology Genetic Approach Identifies Serotonin Pathway as a Possible Target for Obstructive Sleep Apnea: Results from a Literature Search Review
Sleep Disorders·2017· 21 citedOpen Access
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells
Toxicology Research·2017· 10 citedOpen Access
Oxidative Stress Under Ambient and Physiological Oxygen Tension in Tissue Culture
Current Pharmacology Reports·2016· 137 citedOpen Access
Nuclear Factor κB1/RelA Mediates Inflammation in Human Lung Epithelial Cells at Atmospheric Oxygen Levels
Journal of Cellular Physiology·2015· 8 citedOpen Access
A Mycobacterial Phosphoribosyltransferase Promotes Bacillary Survival by Inhibiting Oxidative Stress and Autophagy Pathways in Macrophages and Zebrafish
Journal of Biological Chemistry·2015· 40 citedOpen Access
Epigenetic dysregulation by nickel through repressive chromatin domain disruption
Proceedings of the National Academy of Sciences·2014· 48 citedOpen Access
Rat brain myo-inositol 3-phosphate synthase is a phosphoprotein
Molecular and Cellular Biochemistry·2013· 12 cited
Insulin Activates JNK in Primary Rat Hepatocytes
Journal of Surgical Research·2013
The role of antioxidants and other agents in alleviating hyperglycemia mediated oxidative stress and injury in liver
Food & Function·2013· 129 cited
Drug repositioning of latent TB
International Journal of Infectious Diseases·2012Open Access
Role of glycans and glycoproteins in disease development by<i>Mycobacterium tuberculosis</i>
Critical Reviews in Microbiology·2012· 27 cited
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Frequent Co-authors

Suresh Cuddapah(6), Cynthia C. Jose(5), Babi Ramesh Reddy Nallamilli(4), Madhuri Hegde(4), Vinay Singh Tanwar(3), Xiaoru Zhang(3), Vinish Ramachander(3), Lora Jh Bean(3), Sulagna Banerjee(3), Max Costa(2), Aparajita Dey(2), Ratnam S. Seelan(2), Ranga N. Parthasarathy(2), Zeqiang Ma(2), Soumitra Mohanty(2), Ramesh Kumar Gopal(2), Avinash Sonawane(2), Carolina Gonzalez-Cavazos(2), Anna Tanska(2), Michael Mayers(2)