Isabelle Desbaillets

École Polytechnique Fédérale de Lausanne — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index3.0kcitations26works0.02yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(9), Glioma Diagnosis and Treatment(6), Mitochondrial Function and Pathology(4), Immune cells in cancer(4), Pluripotent Stem Cells Research(3)

Publications25 total

Report from the 2017 Annual SGV Meeting
Laboratory Animals·2018Open Access
Modulation of Angiogenic and Inflammatory Response in Glioblastoma by Hypoxia
PLoS ONE·2009· 109 citedOpen Access
Elevated levels of MIC‐1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome
International Journal of Cancer·2009· 97 citedOpen Access
112 Stroma irradiation promotes tumor invasion and metastasis through suppression of angiogenesis and selection of highly invasive tumor cells
Radiotherapy and Oncology·2006
Enhanced response to radiotherapy in tumours deficient in the function of hypoxia-inducible factor-1
Radiotherapy and Oncology·2005· 130 cited
Differentiating Embryonic Stem Cells into Embryoid Bodies
Humana Press eBooks·2004· 115 cited
Classification of human astrocytic gliomas on the basis of gene expression: a correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes.
PubMed·2003· 279 cited
Targeted Disruption of the Mouse PAS Domain Serine/Threonine Kinase PASKIN
Molecular and Cellular Biology·2003· 39 citedOpen Access
Characterization of HIF-1α overexpressing HeLa cells and implications for gene therapy
Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology·2002· 14 cited
Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor
PubMed·2002· 56 citedOpen Access
HIF‐1 is expressed in normoxic tissue and displays an organ‐specific regulation under systemic hypoxia
The FASEB Journal·2001· 719 citedOpen Access
Mammalian PASKIN, a PAS-Serine/Threonine Kinase Related to Bacterial Oxygen Sensors
Biochemical and Biophysical Research Communications·2001· 28 citedOpen Access
Dissecting hypoxia‐dependent and hypoxia‐independent steps in the HIF‐1α activation cascade: implications for HIF‐1α gene therapy
The FASEB Journal·2001· 83 cited
Embryoid bodies: an in vitro model of mouse embryogenesis
Experimental Physiology·2000· 78 cited
Embryoid Bodies: An <i>In Vitro</i> Model of Mouse Embryogenesis
Experimental Physiology·2000· 293 cited
Regulation of interleukin-8 expression by reduced oxygen pressure in human glioblastoma
Oncogene·1999· 113 cited
Up-regulation of hypoxia-inducible factor-1alpha is not sufficient for hypoxic/anoxic p53 induction.
PubMed·1998· 78 cited
Necrogenesis and Fas/APO-1 (CD95) Expression in Primary (de novo) and Secondary Glioblastomas
Journal of Neuropathology & Experimental Neurology·1998· 76 citedOpen Access
Upregulation of Interleukin 8 by Oxygen-deprived Cells in Glioblastoma Suggests a Role in Leukocyte Activation, Chemotaxis, and Angiogenesis
The Journal of Experimental Medicine·1997· 241 citedOpen Access
Human astrocytomas and glioblastomas express monocyte chemoattractant protein‐1 (MCP‐1) <i>in vivo</i> and <i>in vitro</i>
International Journal of Cancer·1994· 142 cited
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Frequent Co-authors

Max Gassmann(9), Nicolas de Tribolet(8), Roland H. Wenger(7), Annie‐Claire Diserens(6), Marie‐France Hamou(6), Erwin G. Van Meir(6), Gisele Höpfl(4), Urs Ziegler(3), Roger Stupp(3), Monika E. Hegi(3), Mitsuhiro Tada(3), Thomas Höfer(3), Steven Brem(3), Peter Groscurth(2), Mauro Delorenzi(2), Kaye J. Williams(2), Ian J. Stratford(2), Anastasia Murat(2), Eugenia Migliavacca(2), Curzio Rüegg(2)