Francisco Ciruela

Universitat de Barcelona — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

70h-index14.3kcitations346works2.92yr avg
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Research Topics

Receptor Mechanisms and Signaling(167), Adenosine and Purinergic Signaling(114), Neuroscience and Neuropharmacology Research(111), Neuropeptides and Animal Physiology(55), Pharmacological Receptor Mechanisms and Effects(31)

Publications346 total

Hypersensitivity of the striatal striosomal dopamine D1 receptor-neuron in a rodent model of restless legs syndrome
2026Open Access
Natural cannabinoids effects on glutamatergic and dopaminergic neurotransmission in a transgenic model of Alzheimer's disease
Alzheimer s & Dementia·2025Open Access
Regulation of the orphan G-protein–coupled receptor GPRC5B by MLC1 and the cell adhesion molecule GlialCAM in megalencephalic leukoencephalopathy
Journal of Biological Chemistry·2025Open Access
Functional significance of opioid receptor homomers and heteromers
Nature Communications·2025· 2 citedOpen Access
Light-Regulated Agonists Spatiotemporally Activating the Vitamin D Receptor Mitigate Psoriasis-like Inflammation in Mice without Inducing Hypercalcemia
ACS Central Science·2025· 1 citedOpen Access
Bitopic A<sub>3</sub> Adenosine Receptor Molecular Probes: Positive Allosteric Modulation and Noncanonical Activation
Journal of Medicinal Chemistry·2025
Repurposed antihypertensive drugs for negative symptoms in schizophrenia: A systematic review and meta‐analysis
Psychiatry and Clinical Neurosciences·2025Open Access
G protein-coupled receptor 37 biomarker potential in Parkinson’s disease: Inflammation might be the hidden trigger
Neural Regeneration Research·2025Open Access
Long-lasting behavioral, molecular and functional connectivity alterations after chronic THC exposure during adolescence in mice
Progress in Neuro-Psychopharmacology and Biological Psychiatry·2025· 1 citedOpen Access
B2R overexpression in resistant prolactinomas promotes B2R-D2R dimerization, with B2R precluding D2R signalling generating resistance to D2R agonists
Endocrine Abstracts·2025
Wireless, battery-free, remote photoactivation of caged-morphine for photopharmacological pain modulation without side effects
Biosensors and Bioelectronics·2025· 3 citedOpen Access
Temporomandibular disorders and mental health: shared etiologies and treatment approaches
The Journal of Headache and Pain·2025· 28 citedOpen Access
The dopaminergic effects of esketamine are mediated by a dual mechanism involving glutamate and opioid receptors
Molecular Psychiatry·2025· 6 citedOpen Access
Striatal dopamine D2, adenosine A2A and cannabinoid CB1 receptors balance as a target against non-cognitive symptoms in a mouse model of Alzheimer's disease
Pharmacology Biochemistry and Behavior·2025Open Access
Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs
Molecular Systems Biology·2025Open Access
Targeting Cannabinoid Receptors Against Neurodegenerative Diseases: NanoLuc Binary Technology and Proximity Ligation In Situ Assay to Evaluate Pharmacological Activity of Novel Compounds and Receptor Heteromerization
Neuromethods·2024
Photoswitchable Diazocine Derivative for Adenosine A<sub>3</sub> Receptor Activation in Psoriasis
Journal of the American Chemical Society·2024· 15 citedOpen Access
Dopamine dynamics in chronic pain: music-induced, sex-dependent, behavioral effects in mice
PAIN Reports·2024· 2 citedOpen Access
343 TREX2 inhibitors: a breakthrough keratinocyte-based therapy for psoriasis
Journal of Investigative Dermatology·2024· 1 cited
B2R-D2R Interaction in Prolactinomas and Nonfunctional Adenomas: Impact on Dopamine Resistance
Endocrinology·2024· 4 citedOpen Access
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Frequent Co-authors

Rafael Franco(29), Sergi Ferré(20), Kjell Fuxé(19), Vicent Casadó(15), Luigi F. Agnati(15), Carme Lluı́s(14), Josefa Mallol(13), Carmen Lluís(12), Enric I. Canela(11), Dasiel O. Borroto‐Escuela(9), Daniel Marcellino(8), Wilber Romero‐Fernandez(8), Javier Burgueño(7), Meritxell Canals(7), Amina S. Woods(7), Víctor Fernández‐Dueñas(7), Alexander O. Tarakanov(7), Steven R. Goldberg(6), Rodrigo A. Cunha(5), Patrizia Popoli(4)