Katherine S. H. Beckham

European Molecular Biology Laboratory — Germany

Medicine · Health Sciences

12h-index632citations21works0.02yr avg
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Research Topics

Tuberculosis Research and Epidemiology(7), Mycobacterium research and diagnosis(7), Enzyme Structure and Function(6), Bacterial Genetics and Biotechnology(4), Antibiotic Resistance in Bacteria(4)

Publications21 total

C25-modified rifamycin derivatives with improved activity against <i>Mycobacterium abscessus</i>
PNAS Nexus·2022· 14 citedOpen Access
Crystal structures of WrbA, a spurious target of the salicylidene acylhydrazide inhibitors of type III secretion in Gram-negative pathogens, and verification of improved specificity of next-generation compounds
Microbiology·2022· 1 citedOpen Access
C25-modified rifamycin derivatives with improved activity against <i>Mycobacterium abscessus</i>
2021Open Access
Conserved and specialized functions of Type VII secretion systems in non-tuberculous mycobacteria
Microbiology·2021· 29 citedOpen Access
Structure of the mycobacterial ESX-5 type VII secretion system pore complex
Science Advances·2021· 60 citedOpen Access
Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex
2020· 6 citedOpen Access
The <scp>pMy</scp> vector series: A versatile cloning platform for the recombinant production of mycobacterial proteins in <i>Mycobacterium smegmatis</i>
Protein Science·2020· 9 citedOpen Access
The ATPases of the mycobacterial type VII secretion system: Structural and mechanistic insights into secretion
Progress in Biophysics and Molecular Biology·2019· 24 citedOpen Access
An NAD+ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death
Molecular Cell·2019· 82 citedOpen Access
Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis
Nature Microbiology·2017· 119 citedOpen Access
From screen to target: insights and approaches for the development of anti-virulence compounds
Frontiers in Cellular and Infection Microbiology·2014· 25 citedOpen Access
Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103<sup>+</sup>CD11b<sup>+</sup><scp>DC</scp>s in the intestinal lamina propria
European Journal of Immunology·2014· 30 citedOpen Access
The metabolic enzyme <scp>AdhE</scp> controls the virulence of <scp><i>E</i></scp><i>scherichia coli</i> <scp>O</scp>157:<scp>H</scp>7
Molecular Microbiology·2014· 58 citedOpen Access
Express Your LOV: An Engineered Flavoprotein as a Reporter for Protein Expression and Purification
PLoS ONE·2012· 37 citedOpen Access
The structure of an orthorhombic crystal form of a `forced reduced' thiol peroxidase reveals lattice formation aided by the presence of the affinity tag
Acta Crystallographica Section F Structural Biology and Crystallization Communications·2012· 4 citedOpen Access
FolX from <i>Pseudomonas aeruginosa</i> is octameric in both crystal and solution
FEBS Letters·2012· 3 citedOpen Access
Structural Characterisation of Tpx from Yersinia pseudotuberculosis Reveals Insights into the Binding of Salicylidene Acylhydrazide Compounds
PLoS ONE·2012· 20 citedOpen Access
High-Throughput Methods for the Identification of Protein Purification Conditions Using a Cleavable Tag System
Methods in cell biology·2012· 2 cited
Identification of Bacterial Target Proteins for the Salicylidene Acylhydrazide Class of Virulence-blocking Compounds
Journal of Biological Chemistry·2011· 94 citedOpen Access
Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from<i>Yersinia pseudotuberculosis</i>
Acta Crystallographica Section F Structural Biology and Crystallization Communications·2010· 7 citedOpen Access
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Frequent Co-authors

Andrew J. Roe(10), Matthias Wilmanns(9), Mads Gabrielsen(8), Annabel Parret(5), Olwyn Byron(5), Dai Wang(4), Mikael Elofsson(4), Mandy Rettel(3), Mikhail M. Savitski(3), Caroline E. Zetterström(3), Christina Ritter(3), Flor Vásquez Sotomayor(3), Matt D. Johansen(3), Laurent Kremer(3), Florian P. Maurer(3), Sonja Staack(3), Dmitri I. Svergun(2), David L. Gally(2), Richard Burchmore(2), Brian O. Smith(2)