Lukasz J. Bugaj

California Institute for Regenerative Medicine — United States

Neuroscience · Life Sciences

21h-index2.3kcitations67works5.32yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Photoreceptor and optogenetics research(19), Light effects on plants(17), Photosynthetic Processes and Mechanisms(8), Microtubule and mitosis dynamics(8), Nitric Oxide and Endothelin Effects(6)

Publications67 total

Optogenetic Translocation to Subcellular Compartments through Regulation of Protein Avidity
ACS Synthetic Biology·2026
Abstract A003: Adaptor sequestration and drug-induced potentiation of EGFR are widespread features of oncogenic RTK fusions
Cancer Research·2026
Abstract B007: Low-order assemblies drive RTK fusion signaling without condensation
Cancer Research·2026
EGFR suppression and drug-induced potentiation are widespread features of oncogenic RTK fusions
2025
Nuclear-import receptors remodel the dilute phase to suppress phase transitions of RNA-binding proteins with prion-like domains
2025Open Access
Quantifying cancer- and drug-induced changes in Shannon information capacity of RTK signaling
Scientific Reports·2025Open Access
Quantifying cancer- and drug-induced changes in Shannon information capacity of RTK signaling
2025· 2 citedOpen Access
Optogenetic translocation to subcellular compartments through regulation of protein avidity
2025Open Access
Abstract LB450: Dissecting the role of condensation in signaling from RTK fusion oncoproteins
Cancer Research·2025
Intramolecular competition generates pulsatory protein activity shaped by light, temperature, and evolution
2025· 1 citedOpen Access
Multiplexed dynamic control of temperature to probe and observe mammalian cells
Cell Systems·2025· 2 cited
BPS2025 - Chaperoning functions of beta-importin TNPO1 are realized by its ability to modulate the phase behaviors of cargo proteins
Biophysical Journal·2025
A temperature-inducible protein module for control of mammalian cell fate
Nature Methods·2025· 14 citedOpen Access
Oncogenic EML4-ALK assemblies suppress growth factor perception and modulate drug tolerance
Nature Communications·2024· 12 citedOpen Access
Optogenetic Control of Condensates: Principles and Applications
Journal of Molecular Biology·2024· 5 cited
Lipid-mediated intracellular delivery of recombinant bioPROTACs for the rapid degradation of undruggable proteins
Nature Communications·2024· 44 citedOpen Access
Simple visualization of submicroscopic protein clusters with a phase-separation-based fluorescent reporter
Cell Systems·2024Open Access
Multiplexed dynamic control of temperature to probe and observe mammalian cells
2024· 4 citedOpen Access
A temperature-inducible protein module for control of mammalian cell fate
2024· 5 citedOpen Access
Simple visualization of submicroscopic protein clusters with a phase-separation-based fluorescent reporter
Cell Systems·2024· 16 citedOpen Access
page 1 of 4Next →

Frequent Co-authors

William Benman(14), Thomas R. Mumford(11), David V. Schaffer(8), Brian Y. Chow(8), David Gonzalez-Martinez(8), Zikang Huang(8), Ravi S. Kane(5), Wendell A. Lim(5), Sungwoo Ryoo(4), Daniel Nyhan(4), Artin A. Shoukas(4), Dan E. Berkowitz(4), Erin E. Berlew(4), Ivan A. Kuznetsov(4), Ayush Aditya Pal(4), Juan Guan(4), L. E. Roth(4), Pavan Iyengar(4), Lakshmi Santhanam(3), Trever G. Bivona(3)