Caroline Staib

Helmholtz Zentrum München — Germany

Immunology and Microbiology · Life Sciences

23h-index2.4kcitations38works0.02yr avg
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Research Topics

Poxvirus research and outbreaks(16), Herpesvirus Infections and Treatments(12), Virus-based gene therapy research(10), Immunotherapy and Immune Responses(8), DNA Repair Mechanisms(6)

Publications35 total

Viral host-range factor C7 or K1 is essential for modified vaccinia virus Ankara late gene expression in human and murine cells, irrespective of their capacity to inhibit protein kinase R-mediated phosphorylation of eukaryotic translation initiation factor 2 
Journal of General Virology·2009· 42 cited
The Orthopoxvirus 68-Kilodalton Ankyrin-Like Protein Is Essential for DNA Replication and Complete Gene Expression of Modified Vaccinia Virus Ankara in Nonpermissive Human and Murine Cells
Journal of Virology·2009· 22 citedOpen Access
Marker gene swapping facilitates recombinant Modified Vaccinia Virus Ankara production by host-range selection
Journal of Virological Methods·2008· 30 cited
Vaccination with a Modified Vaccinia Virus Ankara‐based vaccine protects mice from allergic sensitization
The Journal of Gene Medicine·2008· 12 cited
A prime-boost vaccination protocol optimizes immune responses against the nucleocapsid protein of the SARS coronavirus
Vaccine·2008· 28 citedOpen Access
In vivo attenuation of recombinant murine gammaherpesvirus 68 (MHV-68) is due to the expression and immunogenicity but not to the insertion of foreign sequences
Virology·2008· 7 cited
The human spleen is a major reservoir for long-lived vaccinia virus–specific memory B cells
Blood·2008· 177 citedOpen Access
Protective vaccination with hepatitis C virus NS3 but not core antigen in a novel mouse challenge model
The Journal of Gene Medicine·2007· 18 cited
Evaluation of Modified Vaccinia Virus Ankara as an Alternative Vaccine against Smallpox in Chronically HIV Type 1-Infected Individuals Undergoing HAART
AIDS Research and Human Retroviruses·2007· 31 cited
Recombinant murine gammaherpesvirus 68 (MHV-68) as challenge virus to test efficacy of vaccination against chronic virus infections in the mouse model
Vaccine·2007· 13 cited
Vaccine-induced early control of hepatitis C virus infection in chimpanzees fails to impact on hepatic PD-1 and chronicity
Hepatology·2007· 90 citedOpen Access
Short-term, but not post-exposure, protection against lethal orthopoxvirus challenge after immunization with modified vaccinia virus Ankara
Journal of General Virology·2006· 40 cited
Inactivation of the viral interleukin 1  receptor improves CD8+ T-cell memory responses elicited upon immunization with modified vaccinia virus Ankara
Journal of General Virology·2005· 87 cited
Protective CD8 T Cell Immunity Triggered by CpG-Protein Conjugates Competes with the Efficacy of Live Vaccines
The Journal of Immunology·2005· 102 citedOpen Access
Role of Viral Factor E3L in Modified Vaccinia Virus Ankara Infection of Human HeLa Cells: Regulation of the Virus Life Cycle and Identification of Differentially Expressed Host Genes
Journal of Virology·2005· 49 citedOpen Access
Modified vaccinia virus Ankara as antigen delivery system: how can we best use its potential?
Current Opinion in Biotechnology·2004· 162 citedOpen Access
Neutralization Assay Using a Modified Vaccinia Virus Ankara Vector Expressing the Green Fluorescent Protein Is a High-Throughput Method To Monitor the Humoral Immune Response against Vaccinia Virus
Clinical and Vaccine Immunology·2004· 37 citedOpen Access
Construction and Isolation of Recombinant MVA
Humana Press eBooks·2004· 98 cited
Live Viral Vectors: Vaccinia Virus
Humana Press eBooks·2003· 24 cited
Vaccinia Vectors as Candidate Vaccines: The Development of Modified Vaccinia Virus Ankara for Antigen Delivery
Current Drug Targets - Infectious Disorders·2003· 190 cited
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Frequent Co-authors

Gerd Sutter(23), Volker Erfle(9), Friedrich Grummt(8), Ingo Drexler(4), Michael Schmid(4), Antonio Cosma(3), Dirk H. Busch(3), I. Nanda(3), Susanne El‐Gogo(3), Heiko Adler(3), Marianne Löwel(2), Marcus Meyr(2), Juan José Lasarte(2), JÜRGEN PESCH(2), Ursula Brehm(2), Sigrid Kisling(2), Holger Ludwig(2), Karin M. Sperling(2), Astrid Schwantes(2), Yasemin Suezer(2)