Manuel F. Juette

Cornell University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index2.7kcitations28works0.02yr avg
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Research Topics

RNA and protein synthesis mechanisms(14), Advanced Fluorescence Microscopy Techniques(14), RNA modifications and cancer(10), Bacterial Genetics and Biotechnology(4), Advanced Electron Microscopy Techniques and Applications(4)

Publications28 total

Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes
eLife·2022· 26 citedOpen Access
Author response: Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes
2022Open Access
Didemnin B and ternatin-4 inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes
2022Open Access
Endogenously Encoded Ribosomal RNA Sequence Variation within the Assemble Ribosome can Regulate Stress Response Gene Expression and Phenotype
Biophysical Journal·2019· 1 citedOpen Access
Endogenous rRNA Sequence Variation Can Regulate Stress Response Gene Expression and Phenotype
Cell Reports·2018· 114 citedOpen Access
Single-molecule analysis of ligand efficacy in β2AR–G-protein activation
Nature·2017· 345 citedOpen Access
Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome
Proceedings of the National Academy of Sciences·2016· 61 citedOpen Access
Single-molecule imaging of non-equilibrium molecular ensembles on the millisecond timescale
Nature Methods·2016· 287 citedOpen Access
Functional Dynamics within the Human Ribosome Regulate the Rate of Active Protein Synthesis
Molecular Cell·2015· 81 citedOpen Access
Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A
Molecular Cell·2015· 93 citedOpen Access
Imaging Functional Dynamic Processes within Integral Membrane Proteins at the Single‐Molecule Scale
The FASEB Journal·2015· 1 cited
Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic Hygromycin A, mRNA and three tRNAs in the A, P and E sites at 2.6A resolution
2015
Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the <i>Escherichia coli</i> ribosome
Proceedings of the National Academy of Sciences·2014· 47 citedOpen Access
Crystal structure of the E. coli ribosome bound to negamycin.
2014
Crystal structure of the E. coli ribosome bound to negamycin. This file contains the 50S subunit of the first 70S ribosome.
2014
Crystal structure of the E. coli ribosome bound to negamycin. This file contains the 30S subunit of the first 70S ribosome.
2014
Crystal structure of the E. coli ribosome bound to negamycin. This file contains the 50S subunit of the second 70S ribosome.
2014
The bright future of single-molecule fluorescence imaging
Current Opinion in Chemical Biology·2014· 126 cited
Ultra-stable organic fluorophores for single-molecule research
Chemical Society Reviews·2013· 391 citedOpen Access
Adaptive optics enables three-dimensional single particle tracking at the sub-millisecond scale
Applied Physics Letters·2013· 15 citedOpen Access
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Frequent Co-authors

Scott C. Blanchard(19), Russ B. Altman(14), Joerg Bewersdorf(8), Daniel S. Terry(8), Michael Wasserman(7), Zhou Zhou(5), N.B. Olivier(5), J. Noeske(5), Gregory S. Basarab(5), Erin Code(5), Ning Gao(5), Stephania Livchak(5), M.D. Miller(5), D. Bryan Prince(5), J.H.D. Cate(5), Ed T. Buurman(5), Angelica Ferguson(4), A.D. Ferguson(4), Jie-Sheng Huang(4), Michael J. Mlodzianoski(3)