Robert K. Bradley

University of Washington — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

52h-index18.6kcitations191works5.32yr avg
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Research Topics

RNA Research and Splicing(80), RNA modifications and cancer(65), Acute Myeloid Leukemia Research(39), RNA and protein synthesis mechanisms(36), Muscle Physiology and Disorders(18)

Publications178 total

Mutant SRSF2-associated impaired erythropoiesis is defined by increased mTORC1 signaling due to FYN missplicing
Leukemia·2026
Development of synthetic introns for selective elimination of U2AF1 mutant MDS
Blood·2025Open Access
Generative genomics accurately predicts future experimental results
2025Open Access
An Isoform-Specific RUNX1C–BTG2 Axis Governs AML Quiescence and Chemoresistance
Blood Cancer Discovery·2025· 1 citedOpen Access
Chorionic Gonadotropin Beta 7 is a marker of immune evasion in cancer
2025· 1 citedOpen Access
Muscleblind-like proteins are novel modulators of the tumor-immune microenvironment
PLoS ONE·2025· 1 citedOpen Access
Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias
Cell·2025· 24 citedOpen Access
Distinct routes of clonal progression in SF3B1-mutant myelodysplastic syndromes
Blood Advances·2025· 4 citedOpen Access
RBM10 loss promotes metastases by aberrant splicing of cytoskeletal and extracellular matrix mRNAs
The Journal of Experimental Medicine·2025· 6 citedOpen Access
CAR T-Cell Therapy for Acute Myeloid Leukemia: Critical Role for TNFα Signaling to Overcome Target Antigen Heterogeneity
Transplantation and Cellular Therapy·2025
Altered Protein Structures and Neoepitopes in Lupus Neutrophils From Dysregulated Splicing of Messenger <scp>RNA</scp>
ACR Open Rheumatology·2025Open Access
Abstract A005: <i>APC</i> mutations dysregulate alternative polyadenylation in cancer
Molecular Cancer Therapeutics·2024
Abstract I002: Alternative polyadenylation as a therapeutic target in cancer
Molecular Cancer Therapeutics·2024
Mis-Splicing Derived Neoantigens and Cognate T Cell Receptors in Splicing Factor Mutant Myeloid Neoplasms
Blood·2024· 1 cited
TNFα Apoptotic Signaling By Antigen-Engaged CAR T-Cells Mediates Clearance of Target Antigen-Negative Acute Myeloid Leukemia
Blood·2024Open Access
APC mutations dysregulate alternative polyadenylation in cancer
Genome biology·2024· 5 citedOpen Access
Supplementary Figures from Mis-splicing of Mitotic Regulators Sensitizes SF3B1-Mutated Human HSCs to CHK1 Inhibition
2024Open Access
Data from Mis-splicing of Mitotic Regulators Sensitizes SF3B1-Mutated Human HSCs to CHK1 Inhibition
2024Open Access
Supplemental Table 3 from Mis-splicing of Mitotic Regulators Sensitizes SF3B1-Mutated Human HSCs to CHK1 Inhibition
2024Open Access
Supplemental Table 3 from Mis-splicing of Mitotic Regulators Sensitizes SF3B1-Mutated Human HSCs to CHK1 Inhibition
2024Open Access
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Frequent Co-authors

Omar Abdel‐Wahab(17), Heidi Dvinge(10), Jose Mario Bello Pineda(6), Eun Hee Kim(5), Stanley Chun-Wei Lee(5), Hana Cho(5), Benjamin H. Durham(5), Akihide Yoshimi(5), Justin Taylor(5), Austin M. Gabel(5), Daichi Inoue(5), Bo Liu(5), Joseph Pangallo(5), Khrystyna North(5), Janine O. Ilagan(4), Alessandro Pastore(4), Sydney X. Lu(4), James D. Thomas(4), Simon J. Hogg(4), Caroline Erickson(4)