Kei‐ichi Sugiyama

National Institute of Occupational Safety and Health — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

27h-index3.0kcitations165works0.82yr avg
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Research Topics

Carcinogens and Genotoxicity Assessment(37), Hepatocellular Carcinoma Treatment and Prognosis(14), Mycotoxins in Agriculture and Food(14), Hepatitis C virus research(12), DNA Repair Mechanisms(11)

Publications165 total

Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment
Regulatory Toxicology and Pharmacology·2025· 1 citedOpen Access
Mitomycin C-induced DNA double-strand breaks are enhanced by catalytical inactivation of DNA polymerase κ in mice
Genes and Environment·2025Open Access
Summary of major conclusions from the 8th International Workshop on Genotoxicity Testing (IWGT), Ottawa, Canada
2025Open Access
Whole genome mutagenicity evaluation using Hawk-Seq™ demonstrates high inter-laboratory reproducibility and concordance with the transgenic rodent gene mutation assay
Genes and Environment·2025· 1 citedOpen Access
Increased mutagenicity in the liver of MutaMouse females following oral treatment with commercial-grade toluene diisocyanate
Genes and Environment·2025Open Access
Effects of carminic acid on gene expressions under epigenetic regulation
Biochemistry and Biophysics Reports·2025Open Access
Verification of health-based guidance values for carbendazim
Regulatory Toxicology and Pharmacology·2025
Dual-directional epi-genotoxicity assay for assessing chemically induced epigenetic effects utilizing the housekeeping TK gene
Scientific Reports·2025· 1 citedOpen Access
Dual-directional epi-genotoxicity assay for assessing chemically induced epigenetic effects utilizing the housekeeping TK gene
2025Open Access
Ames mutagenicity of 15 aryl, benzyl, and aliphatic ring N-nitrosamines
Regulatory Toxicology and Pharmacology·2024· 3 citedOpen Access
Local QSAR based on quantum chemistry calculations for the stability of nitrenium ions to reduce false positive outcomes from standard QSAR systems for the mutagenicity of primary aromatic amines
Genes and Environment·2024· 1 citedOpen Access
Effect of sequencing platforms on the sensitivity of chemical mutation detection using Hawk-Seq™
Genes and Environment·2024· 2 citedOpen Access
Lack of in vivo mutagenicity of carbendazim in the liver and glandular stomach of MutaMice
Genes and Environment·2024· 2 citedOpen Access
Considerations for the genotoxicity assessment of middle size peptide drugs containing non-canonical amino acid residues
Genes and Environment·2023· 2 citedOpen Access
Evaluation of QSAR models for predicting mutagenicity: outcome of the Second Ames/QSAR international challenge project
SAR and QSAR in environmental research·2023· 19 citedOpen Access
Detection of in vivo mutagenicity in rat liver samples using error-corrected sequencing techniques
Genes and Environment·2023· 5 citedOpen Access
In vivo mutagenicity assessment of orally treated tert-butyl hydroperoxide in the liver and glandular stomach of MutaMouse
Genes and Environment·2023· 2 citedOpen Access
P03-12: In vivo mutagenicity assessment and derivation of reference dose of styrene
Toxicology Letters·2023
Curation of more than 10,000 Ames test data used in the Ames/QSAR International Challenge Projects
Elsevier eBooks·2023· 1 cited
List of contributors
Elsevier eBooks·2023
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Frequent Co-authors

Takashi Kumada(14), Seiki Kiriyama(14), Isao Takeda(13), Hidenori Toyoda(10), Satoshi Nakano(9), Toshimasa Osada(8), Yoshiko Sugita‐Konishi(8), Yasuhiro Sone(6), Masamitsu Honma(6), Yoshiharu Inoue(5), Shingo Izawa(5), Atsushi Hakura(5), Masashi Muroi(5), Yoichi Kamata(5), Ken‐ichi Tanamoto(5), Masayuki Kato(4), Yasuhiro Hisanaga(4), Akira Kimura(3), Dan D. Levy(3), Patricia A. Escobar(3)