François Christen

Roche (Switzerland) — Switzerland

Medicine · Health Sciences

4h-index125citations18works0.02yr avg
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Research Topics

Cancer Immunotherapy and Biomarkers(11), Cancer, Hypoxia, and Metabolism(8), Peptidase Inhibition and Analysis(7), Nanoplatforms for cancer theranostics(4), Immune cells in cancer(4)

Publications18 total

Defining therapeutic chimerism thresholds for comprehensive sickle cell disease correction in the townes mouse model
Blood·2025Open Access
Supplementary Figures 1-6 from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Supplementary Table 2 from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Supplementary Table 3 from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Supplementary Table 2 from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Data from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Data from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Supplementary material and methods from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Supplementary Figures 1-6 from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Supplementary material and methods from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Supplementary Table 3 from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Supplementary Table 1 from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Supplementary Table 1 from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
2023Open Access
Novel in Vivo and in Vitro Pharmacokinetic/Pharmacodynamic-Based Human Starting Dose Selection for Glofitamab
Journal of Pharmaceutical Sciences·2021· 29 cited
Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
Clinical Cancer Research·2021· 57 citedOpen Access
DNA Damage Response of 4-Chloro-Ortho-Toluidine in Various Rat Tissues
Toxicological Sciences·2018· 4 cited
Assessment of Preclinical Liver and Skeletal Muscle Biomarkers Following Clofibrate Administration in Wistar Rats
Toxicologic Pathology·2017· 8 citedOpen Access
Effects of GlyT1 inhibition on erythropoiesis and iron homeostasis in rats
Experimental Hematology·2016· 27 cited

Frequent Co-authors

Eva Sum(13), Moritz Rapp(13), Philipp Fröbel(13), Marine Le Clech(13), Harald Dürr(13), Anna Maria Giusti(13), Mario Perro(13), Dario Speziale(13), Leo Kunz(13), Elena Menietti(13), Peter Brünker(13), Ulrike Hopfer(13), Martin Lechmann(13), Andrzej Sobieniecki(13), Birte Appelt(13), Valeria Nicolini(13), Anne Freimoser–Grundschober(13), Whitney Jordaan(13), Sara Labiano(13), Felix Weber(13)