Paola Defilippi

Torino e-district — Italy

Medicine · Health Sciences

48h-index8.7kcitations147works1.62yr avg
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Research Topics

Cell Adhesion Molecules Research(59), Cellular Mechanics and Interactions(27), HER2/EGFR in Cancer Research(19), Monoclonal and Polyclonal Antibodies Research(19), Neuroscience and Neuropharmacology Research(9)

Publications147 total

KIAA1217/SKT and its paralog p140Cap are centrosomal proteins that regulate ciliogenesis through Src family signaling pathway
2025Open Access
The adaptor protein SKT interacts with PSD-95 and SHANK3 and affects synaptic functions
Cell Reports·2025· 1 citedOpen Access
A biophysical and molecular characterization of the interaction between the Alzheimer risk factor BIN1 and the neuronal scaffold protein p140Cap
Journal of Biological Chemistry·2025Open Access
The Role of Extracellular Vesicles in Mediating Signaling in Biliary Epithelial Cell Activation and Cholangiopathies
Cells·2025· 1 citedOpen Access
A breast cancer <scp>PDX</scp> collection enriched in luminal (<scp>ER</scp><sup>+</sup>) tumors and young premenopausal patients to identify new therapeutic strategies for high‐risk patients<sup>†</sup>
The Journal of Pathology·2025· 1 citedOpen Access
RICTOR/mTORC2 downregulation in BRAFV600E melanoma cells promotes resistance to BRAF/MEK inhibition
Molecular Cancer·2024· 8 citedOpen Access
p140Cap regulation of Wnt β-catenin signaling pathway: molecular mechanisms
Digital Access to Libraries·2024
p140Cap modulates the mevalonate pathway decreasing cell migration and enhancing drug sensitivity in breast cancer cells
Cell Death and Disease·2023· 11 citedOpen Access
p140Cap inhibits β-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response
Nature Communications·2023· 13 citedOpen Access
Supplementary Materials and Figures 1-3 from p130Cas as a New Regulator of Mammary Epithelial Cell Proliferation, Survival, and HER2-Neu Oncogene–Dependent Breast Tumorigenesis
2023Open Access
Data from p130Cas as a New Regulator of Mammary Epithelial Cell Proliferation, Survival, and HER2-Neu Oncogene–Dependent Breast Tumorigenesis
2023Open Access
Supplementary Materials and Figures 1-3 from p130Cas as a New Regulator of Mammary Epithelial Cell Proliferation, Survival, and HER2-Neu Oncogene–Dependent Breast Tumorigenesis
2023Open Access
Data from p130Cas as a New Regulator of Mammary Epithelial Cell Proliferation, Survival, and HER2-Neu Oncogene–Dependent Breast Tumorigenesis
2023Open Access
Docking protein p130Cas regulates acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis
Pancreatology·2022· 1 cited
miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression
Cellular and Molecular Life Sciences·2022· 21 citedOpen Access
p140Cap Controls Female Fertility in Mice Acting via Glutamatergic Afference on Hypothalamic Gonadotropin-Releasing Hormone Neurons
Frontiers in Neuroscience·2022· 1 citedOpen Access
STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts
Oncogene·2022· 112 citedOpen Access
Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis
Gastroenterology·2021· 8 citedOpen Access
p130Cas/BCAR1 and p140Cap/SRCIN1 Adaptors: The Yin Yang in Breast Cancer?
Frontiers in Cell and Developmental Biology·2021· 10 citedOpen Access
Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis
Acta Neuropathologica Communications·2021· 32 citedOpen Access
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Frequent Co-authors

Guido Tarone(23), Lorenzo Silengo(17), Sara Cabodi(15), Paola Di Stefano(11), Emilia Turco(11), Mascia Venturino(6), Laura Moro(5), Elisabetta Boeri Erba(5), Virginia Morello(5), Elena Bergatto(4), E Turco(4), Daniele Repetto(4), Annarosa Arcangeli(4), Maria Felice Brizzi(3), Saverio Francesco Retta(3), Federica Cavallo(3), Serena Pillozzi(3), Olivia Crociani(3), Agata A. Tinnirello(3), Brigitte Bisarò(3)