Lee K. Hoong

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index967citations20works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(7), Asymmetric Synthesis and Catalysis(4), Organoboron and organosilicon chemistry(4), Cell Adhesion Molecules Research(3), Carbohydrate Chemistry and Synthesis(3)

Publications20 total

Discovery of Novel Phenolic Antioxidants as Inhibitors of Vascular Cell Adhesion Molecule-1 Expression for Use in Chronic Inflammatory Diseases
Journal of Medicinal Chemistry·2004· 28 citedOpen Access
Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-α-induced VCAM-1 expression
Bioorganic & Medicinal Chemistry Letters·2004· 24 citedOpen Access
Lead Discovery of α,β‐Unsaturated Sulfones from a Combinatorial Library as Inhibitors of Inducible VCAM‐1 Expression.
ChemInform·2003
AGI-1067: A Multifunctional Phenolic Antioxidant, Lipid Modulator, Anti-Inflammatory and Antiatherosclerotic Agent
Journal of Pharmacology and Experimental Therapeutics·2003· 87 cited
Lead discovery of α,β-Unsaturated sulfones from a combinatorial library as inhibitors of inducible VCAM-1 expression
Bioorganic & Medicinal Chemistry Letters·2003· 53 cited
Novel phenolic antioxidants as multifunctional inhibitors of inducible VCAM-1 expression for use in atherosclerosis
Bioorganic & Medicinal Chemistry Letters·2002· 57 citedOpen Access
Nitrobenzene Compounds Inhibit Expression of VCAM-1
Bioorganic & Medicinal Chemistry Letters·2001· 6 citedOpen Access
ChemInform Abstract: Enzyme‐Mediated Enantioselective Preparation of Pure Enantiomers of the Antiviral Agent 2′,3′‐Dideoxy‐5‐fluoro‐3′‐thiacytidine (FTC) (I) and Related Compounds.
ChemInform·1993· 8 cited
Enzyme-mediated enantioselective preparation of pure enantiomers of the antiviral agent 2',3'-dideoxy-5-fluoro-3'-thiacytidine (FTC) and related compounds
The Journal of Organic Chemistry·1992· 96 cited
ChemInform Abstract: Asymmetric Synthesis Using Tartrate Ester Modified Allylboronates. Part 1. Factors Influencing Stereoselectivity.
ChemInform·1990
ChemInform Abstract: Asymmetric Synthesis Using Tartrate Ester‐Modified Allylboronates. Part 2. Single and Double Asymmetric Reactions with Alkoxy‐Substituted Aldehydes.
ChemInform·1990
ChemInform Abstract: The Asymmetric Allylboration Reaction: Dependence of Rate and Enantioselectivity on the Chiral Auxiliary.
ChemInform·1990
Asymmetric synthesis using tartrate ester modified allylboronates. 2. Single and double asymmetric reactions with alkoxy-substituted aldehydes
The Journal of Organic Chemistry·1990· 127 cited
Asymmetric synthesis using tartrate ester modified allylboronates. 1. Factors influencing stereoselectivity
The Journal of Organic Chemistry·1990· 131 cited
The asymmetric allylboration reaction: Dependence of rate and enantioselectivity on the chiral auxiliary
Tetrahedron Letters·1989· 24 cited
Synthetic and mechanistic investigations of the aldehyde addition reactions of tartrate ester modified allylboronates
DSpace@MIT (Massachusetts Institute of Technology)·1989Open Access
ChemInform Abstract: Analytical Resolution of Secondary Methyl Ethers by Chiral Complexation Gas Chromatography.
ChemInform·1987
Analytical resolution of secondary methyl ethers by chiral complexation gas chromatography
The Journal of Organic Chemistry·1987· 18 cited
ChemInform Abstract: Diastereo‐ and Enantioselective Aldehyde Addition Reactions of 2‐Allyl‐1,3,2‐dioxaborolane‐4,5‐dicarboxylic Esters, a Useful Class of Tartrate Ester Modified Allylboronates.
Chemischer Informationsdienst·1986
Diastereo- and enantioselective aldehyde addition reactions of 2-allyl-1,3,2-dioxaborolane-4,5-dicarboxylic esters, a useful class of tartrate ester modified allylboronates
Journal of the American Chemical Society·1985· 308 cited

Frequent Co-authors

William Roush(10), Charles Q. Meng(7), Russell R. Hill(7), Patricia K. Somers(6), Uday Saxena(6), Xiaoxiang Zheng(6), Ki‐Ling Suen(5), Michelle Palmer(4), Martin A. Wasserman(4), Elaine M. Marino(4), Cynthia L. Sundell(3), Jacob E. Simpson(3), Charles Kunsch(3), James A. Sikorski(3), Liming Ni(3), Alan E. Walts(2), Jae Chan Park(2), Julie A. Straub(2), Alan D. Palkowitz(2), Luise E. Strange(2)