Letizia Pruccoli

University of Bologna — Italy

Medicine · Health Sciences

18h-index1.0kcitations43works3.42yr avg
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Research Topics

Cholinesterase and Neurodegenerative Diseases(19), Computational Drug Discovery Methods(12), Genomics, phytochemicals, and oxidative stress(8), Alzheimer's disease research and treatments(7), Curcumin's Biomedical Applications(6)

Publications43 total

Exploring the anti-inflammatory activity of sulforaphane metabolites
Pharmacological Reports·2026
Antioxidant and neuroprotective effects of ubiquinol diacetate: Insights from SH-SY5Y cell line and Caenorhabditis elegans models of Parkinson's disease
Experimental and Molecular Pathology·2026Open Access
Rational optimization of D3R/GSK-3β dual target-directed ligands as potential treatment for bipolar disorder: Design, synthesis, X-ray crystallography, molecular dynamics simulations, in vitro ADME, and in vivo pharmacokinetic studies
European Journal of Medicinal Chemistry·2025Open Access
Glycosylation of chrysin with β-d-glucose tetraacetate (LQFM280) enhances its in vitro and in vivo neuroprotective effects against the toxicity induced by 3-nitropropionic acid
Naunyn-Schmiedeberg s Archives of Pharmacology·2024· 1 citedOpen Access
Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson’s disease
Bioorganic Chemistry·2024· 3 citedOpen Access
Antioxidant and Neuroprotective Effects of Fucoxanthin and Its Metabolite Fucoxanthinol: A Comparative In Vitro Study
Current Issues in Molecular Biology·2024· 18 citedOpen Access
A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3- nitropropionic acid in in vitro and in vivo models
Chemico-Biological Interactions·2024· 4 citedOpen Access
Antioxidant and Anti-Melanogenesis Effects of Teucrium chamaedrys L. Cell Suspension Extract and Its Main Phenylethanoid Glycoside in B16-F10 Cells
Plants·2024· 1 citedOpen Access
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease
ACS Chemical Neuroscience·2023· 30 citedOpen Access
Heat stress as a potential risk factor for vitamin D deficiency
Medical Hypotheses·2023· 3 citedOpen Access
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold
European Journal of Medicinal Chemistry·2023· 11 citedOpen Access
Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions
Journal of Clinical Medicine·2023· 5 citedOpen Access
Targeting the Multifaceted Neurotoxicity of Alzheimer's Diseaseby Tailored Functionalisation of the Curcumin Scaffold
SSRN Electronic Journal·2023Open Access
Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease
Bioorganic & Medicinal Chemistry·2022· 10 citedOpen Access
Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation
RSC Medicinal Chemistry·2022· 7 citedOpen Access
Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies
Toxicology·2021· 47 citedOpen Access
Esculetin Provides Neuroprotection against Mutant Huntingtin-Induced Toxicity in Huntington’s Disease Models
Pharmaceuticals·2021· 12 citedOpen Access
New Antioxidant Ingredients from Brewery By-Products for Cosmetic Formulations
Cosmetics·2021· 16 citedOpen Access
Development of New Extracts of Crocus sativus L. By-Product from Two Different Italian Regions as New Potential Active Ingredient in Cosmetic Formulations
Cosmetics·2021· 21 citedOpen Access
Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases
Neurochemical Research·2020· 18 citedOpen Access
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Frequent Co-authors

Andrea Tarozzi(41), Cláudio Viegas(10), Federica Belluti(8), Silvia Gobbi(8), Alessandra Bisi(8), Laurent E. Dardenne(7), Isabella Alvim Guedes(7), Matheus de Freitas Silva(6), Newton G. Castro(6), Angela Rampa(6), Fabiana Morroni(5), Fernanda Motta R. da Silva(5), Fabiana C. Vilela(5), Alexandre Giusti‐Paiva(5), Vanessa Silva Gontijo(5), Rita Maria Concetta Di Martino(5), Angela De Simone(5), Vincenza Andrisano(5), Barbara Pagliarani(5), Giulia Sita(4)