David Gius

The University of Texas Health Science Center at San Antonio — United States

Medicine · Health Sciences

70h-index17.1kcitations264works5.42yr avg
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Research Topics

Sirtuins and Resveratrol in Medicine(68), Mitochondrial Function and Pathology(54), Cancer, Hypoxia, and Metabolism(35), Redox biology and oxidative stress(28), Epigenetics and DNA Methylation(25)

Publications264 total

Identifying TMEM127-deficient pheochromocytomas/paragangliomas via RET overexpression by immunohistochemistry
2026Open Access
CNOT6 deadenylase safeguards postnatal growth and metabolic transition via <i>Fgf21</i> mRNA decay
2026Open Access
Identifying TMEM127-deficient pheochromocytomas/paragangliomas via RET overexpression by immunohistochemistry
2026Open Access
Esomeprazole inhibits proliferation of scleroderma fibroblasts via cell cycle regulation
Frontiers in Pharmacology·2026Open Access
β3-adrenergic receptor agonist causes acute thermogenic metabolic crisis in ACSS1-K635Q knock-in mice
International Journal of Biological Sciences·2026Open Access
GSK3β guides chromosomal repair pathway selection to support BRCA1-independent PARP inhibitor sensitivity
Journal of Clinical Investigation·2025Open Access
Abstract 083: Mitochondrial acetylation of endothelial LCAD and SOD2 promotes female endothelial dysfunction and hypertension
Hypertension·2025
Abstract 094: Acetylation of mitochondrial LCAD and SOD2 promotes metabolic dysfunction, oxidative stress, multi-organ damage and hypertension
Hypertension·2025
Divergent sex-specific effects on a ketogenic diet: Male, but not female, mice exhibit oxidative stress and cellular senescence
Cell Reports·2025· 6 citedOpen Access
Abstract 2501 Manganese superoxide dismutase hyper-acetylation in breast cancer
Journal of Biological Chemistry·2025Open Access
Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered liver lipid metabolism on a ketogenic diet
Free Radical Biology and Medicine·2025· 5 cited
MnSOD non-acetylation mimic knock-in mice exhibit dilated cardiomyopathy
Free Radical Biology and Medicine·2025· 4 citedOpen Access
Acetylated-SOD2 binds to mitochondrial complex IV and alters cellular metabolism
SSRN Electronic Journal·2025Open Access
Inhibition of p53 Ameliorates Adenine-Induced Kidney Injury in Mice
Journal of the American Society of Nephrology·2024
Abstract P354: Endothelial Sirt3 deficiency and SOD2 acetylation voids female protection from hypertension
Hypertension·2024
Ketogenic diet induces p53-dependent cellular senescence in multiple organs
Science Advances·2024· 62 citedOpen Access
Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease
Science Advances·2024· 21 citedOpen Access
Acetyl-CoA Synthetase Short Chain Family Member-1 (ACSS1) acetylation status is an important regulator of adipose tissue thermogenic function
Physiology·2024
Abstract P2125: Melatonin As A Strategy To Mitigate Late Doxorubicin-induced Cardiotoxicity
Circulation Research·2023
Constitutive knock-in of MnSODK68R causes dilated cardiomyopathy and senescence in mice
Physiology·2023
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Frequent Co-authors

Douglas R. Spitz(10), Seong‐Hoon Park(8), Athanassios Vassilopoulos(8), Kheem S. Bisht(6), Chu‐Xia Deng(6), Özkan Özden(5), James B. Mitchell(5), C. Matthew Bradbury(5), J. Daniel Pennington(4), Haiyan Jiang(4), Phuongmai Nguyen(4), Michael N. Sack(4), Yueming Zhu(4), Hyunseok Kim(3), Hyun‐Seok Kim(3), Jianjun Bao(3), John A. Cook(3), Stephanie Markovina(3), Dee Dee Smart(3), David Mattson(3)