Corey R. Hopkins

University of Nebraska Medical Center — United States

Neuroscience · Life Sciences

44h-index5.8kcitations280works1.62yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(61), Receptor Mechanisms and Signaling(53), Ion channel regulation and function(31), Cardiac electrophysiology and arrhythmias(29), Pharmacological Receptor Mechanisms and Effects(19)

Publications280 total

Synthesis and biological characterization of [3.1.0], [3.2.0], [3.3.0], and [3.4.0] bicyclic pyrrolidine analogs as D4 and sigma 1 receptor dual modulators
2026Open Access
Synthesis and biological characterization of [3.1.0], [3.2.0], [3.3.0], and [3.4.0] bicyclic pyrrolidine analogs as D4 and sigma 1 receptor dual modulators
2026Open Access
Synthesis and Biological Characterization of [3.1.0], [3.2.0], [3.3.0], and [3.4.0] Bicyclic Pyrrolidine Analogs as D4 and Sigma 1 Receptor Dual Modulators
SSRN Electronic Journal·2026Open Access
Synthesis and Biological Characterization of 4,4‐Difluoro‐3‐(phenoxymethyl)piperidine Scaffold as Dopamine 4 Receptor (D <sub>4</sub> R) Antagonist in vitro Tool compounds
ChemMedChem·2025· 1 citedOpen Access
Further Structure‐Activity Relationship of G Protein‐Gated Inwardly Rectifying Potassium Channels 1/2 Activators: Synthesis and Biological Characterization of In Vitro Tool Compounds
ChemMedChem·2025Open Access
End-to-End Backbone Cyclization Enhances Passive Permeability of bRo5 Oligomeric Depsipeptides with Nonlinear Size Dependence
ACS Medicinal Chemistry Letters·2025· 3 citedOpen Access
Synthesis and biological characterization of 4,4-difluoro-3-(phenoxymethyl)piperidine scaffold as dopamine 4 receptor (D4R) antagonist in vitro tool compounds
2025Open Access
Update on mGlu4 modulator patents: 2017 to present
Expert Opinion on Therapeutic Patents·2025· 1 cited
Further SAR of GIRK1/2 positive allosteric modulators: Synthesis and Biological Characterization of In Vitro Tool Compounds
2025Open Access
Discovery of VU0467319: an M<sub>1</sub> Positive Allosteric Modulator Candidate That Advanced into Clinical Trials
ACS Chemical Neuroscience·2024· 9 citedOpen Access
Further SAR of GIRK1/2 Activators: In Vitro Biological Characterization and Evaluation of Effects on Neuropathic and Inflammatory Pain in Rodents
2024
Phosphodiesterase 4 (PDE4) and neurological disorders: A promising frontier in neuropharmacology
Advances in pharmacology·2024· 3 cited
The backbone constitution drives passive permeability independent of side chains in depsipeptide and peptide macrocycles inspired by <i>ent</i>-verticilide
Chemical Science·2024· 4 citedOpen Access
P‐BB‐60 | Platelet Dose in LVDS48 Apheresis Platelets, Leukocytes Reduced
Transfusion·2023
CCDC 2194423: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
CCDC 2194422: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Discovery, synthesis and biological evaluation of a series of N-(phenylcarbamothioyl)-2-napthamides as inhibitors of Claudin-1
Bioorganic & Medicinal Chemistry·2023· 4 citedOpen Access
Abstract 1590: Identification and characterization of a first-generation inhibitor of claudin-1 to inhibit colon cancer progression and metastasis
Cancer Research·2023
Discovery, synthesis and biological evaluation of a series of N-(phenylcarbamothioyl)-2-napthamides as inhibitors of Claudin-1
2023Open Access
In Vivo Pharmacokinetic and Pharmacodynamic Properties of the Antiarrhythmic Molecule ent-Verticilide
Journal of Pharmacology and Experimental Therapeutics·2023· 13 citedOpen Access
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Frequent Co-authors

Craig W. Lindsley(34), P. Jeffrey Conn(20), Colleen M. Niswender(17), Darren W. Engers(14), Carrie K. Jones(12), J. Scott Daniels(11), Anna L. Blobaum(10), C. David Weaver(9), Michael R. Wood(7), Owen B. McManus(7), Meng Wu(6), Thomas M. Bridges(6), Haibo Yu(6), Charles C. Hong(5), Ryan D. Morrison(5), Rocio Zamorano(5), Jerod S. Denton(5), Bruce J. Melancon(4), Shunyou Long(4), Michael Bubser(4)