Melba Marie Page

Medicine · Health Sciences

2h-index48citations16works0.02yr avg
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Research Topics

Cancer Immunotherapy and Biomarkers(9), Immune cells in cancer(5), Cancer Cells and Metastasis(3), Ferroptosis and cancer prognosis(3), Cancer Research and Treatments(3)

Publications16 total

Abstract LB-B06: A novel <i>ex vivo</i> 3D tumor organoid model of fresh patient tumors (3D-ACT) to assess efficacy of cellular therapy in immuno-oncology
Molecular Cancer Therapeutics·2019
Abstract 34: A high-content imaging platform for quantitative assessment of immunogenic tumor cell killing and T-cell proliferation in 3D tumoroids of fresh patient tumor samples
Tumor Biology·2019Open Access
Abstract 2546: Impact of CDK4/6 inhibition on tumor immune microenvironment and immunomodulatory effects PD-L1 blockade in a physiologically relevant 3D-tumoroid model of fresh patient tumor tissue<i>ex vivo</i>
Molecular and Cellular Biology / Genetics·2019
Abstract 42: The importance of intact tumor immune microenvironment in unpropagated 3D fresh patient tumoroids in immuno-oncology drug testing for immunogenic tumor cell death and T-cell activation
Tumor Biology·2019Open Access
Abstract 42: The importance of intact tumor immune microenvironment in unpropagated 3D fresh patient tumoroids in immuno-oncology drug testing for immunogenic tumor cell death and T-cell activation
Cancer Research·2019
Abstract 34: A high-content imaging platform for quantitative assessment of immunogenic tumor cell killing and T-cell proliferation in 3D tumoroids of fresh patient tumor samples
Cancer Research·2019
Abstract 2546: Impact of CDK4/6 inhibition on tumor immune microenvironment and immunomodulatory effects PD-L1 blockade in a physiologically relevant 3D-tumoroid model of fresh patient tumor tissue <i>ex vivo</i>
Cancer Research·2019· 2 cited
Abstract 1020: Characterization of the immune landscape and analysis of tumor response after anti-PD-1 blockade in a 3D <i>ex vivo</i> system of non-small lung cancer
Cancer Research·2018· 1 cited
Abstract LB-347: Integrated Comprehensive Analysis of Immune Cell Subsets and Assessment of Checkpoint Inhibitor Response in Head and Neck Squamous Cell Carcinoma, Urothelial Carcinoma and Renal Cell Carcinoma 3D <i>Ex Vivo</i>
Cancer Research·2018· 1 cited
P2.02-030 Bavituximab in Combination With Nivolumab Enhances Tumor Immune Response in a 3D Ex Vivo System of Lung Cancer Patients
Journal of Thoracic Oncology·2017
Effect of bavituximab in combination with nivolumab on tumor immune response in a 3D ex vivo system of lung cancer patients.
Journal of Clinical Oncology·2017· 1 cited
Anti-PD1 treatment to induce M1 polarization of tumor infiltrating macrophages in a 3D ex vivo system of lung cancer patients.
Journal of Clinical Oncology·2017· 12 cited
167 In Vivo Generation of EGFRi Resistance in a Proprietary Patient-derived Xenograft with an Activating EGFR Mutation (L858R); Subsequent Validation in an Orthotopic Lung Model with 3D Optical Tomographic MicroCT Imaging
European Journal of Cancer·2012
568 POSTER Selective inhibition of Met kinase activity impairs metastatic cancer cell motility and survival
European Journal of Cancer Supplements·2008· 1 cited
Vaccine-induced CD4+ T cells against the simian immunodeficiency virus gag protein. Epitope specificity and relevance to protective immunity
The Journal of Immunology·1991· 30 cited
A new derivative for targeting chlorambucil to cancer cells
European Journal of Cancer and Clinical Oncology·1985

Frequent Co-authors

Jenny Kreahling(12), Soner Altiok(12), Melanie Mediavilla-Varela(8), Vijayendra Agrawal(7), Scott Antonia(3), Melanie Mediavilla Varela(3), Bruce Freimark(2), Nikoletta L. Kallinteris(2), Kingston H. G. Mills(1), Amanda Barnard(1), Martin A. K. Williams(1), Changying Ling(1), E. J. Stott(1), P. Silvera(1), F. Taffs(1), A S Kingsman(1), Sally E. Adams(1), Joseph Shan(1), Matthias Versele(1), Tom Lavrijssen(1)