Mervi T. Hyvönen

University of Eastern Finland — Finland

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index1.3kcitations73works0.02yr avg
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Research Topics

Polyamine Metabolism and Applications(57), Amino Acid Enzymes and Metabolism(35), Cannabis and Cannabinoid Research(31), Pancreatic function and diabetes(11), Epigenetics and DNA Methylation(6)

Publications73 total

Role of Polyamine-Induced Dimerization of Antizyme in Its Cellular Functions
International Journal of Molecular Sciences·2022· 8 citedOpen Access
Obesity and hyperinsulinemia drive adipocytes to activate a cell cycle program and senesce
Nature Medicine·2021· 156 cited
α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation
Biomolecules·2021· 3 citedOpen Access
Novel fleximer pyrazole-containing adenosine analogues: chemical, enzymatic and highly efficient biotechnological synthesis
Organic & Biomolecular Chemistry·2021· 11 cited
Synthesis of (3R,10R)- and (3S,10S)-Diastereomers of 3,10-Dimethylspermine
Russian Journal of Bioorganic Chemistry·2020· 1 cited
Chemical activation of SAT1 corrects diet-induced metabolic syndrome
Cell Death and Differentiation·2020· 38 citedOpen Access
Hydroxylamine Analogue of Agmatine: Magic Bullet for Arginine Decarboxylase
Biomolecules·2020· 27 citedOpen Access
Unforeseen Possibilities To Investigate the Regulation of Polyamine Metabolism Revealed by Novel C-Methylated Spermine Derivatives
Journal of Medicinal Chemistry·2019· 9 citedOpen Access
Humanised RadA mutant HumRadA22 in complex with a recombined BRC repeat 8-2
2018
Acetylated derivatives of C-methylated analogues of spermidine: synthesis and interaction with N1-acetylpolyamine oxidase
Mendeleev Communications·2018· 5 cited
Controlling the regioselectivity and stereospecificity of FAD-dependent polyamine oxidases with the use of amine-attached guide molecules as conformational modulators
Bioscience Reports·2018· 6 citedOpen Access
Controlling of<i>N</i>-alkylpolyamine analogue metabolism by selective deuteration
Biochemical Journal·2018· 4 cited
Hepatitis C Virus Alters Metabolism of Biogenic Polyamines by a ROS-dependent Induction of Key Enzymes of Their Metabolism
Free Radical Biology and Medicine·2017
Designed Ankyrin Repeat Protein (DARPin) A4 in complex with Lysozyme
2017
Hepatitis C virus alters metabolism of biogenic polyamines by affecting expression of key enzymes of their metabolism
Biochemical and Biophysical Research Communications·2017· 28 cited
Tailored Dual PEGylation of Inorganic Porous Nanocarriers for Extremely Long Blood Circulation in Vivo
ACS Applied Materials & Interfaces·2016· 52 cited
Tamoxifen metabolite endoxifen interferes with the polyamine pathway in breast cancer
Amino Acids·2016· 15 cited
Abstract 3765: Induction of amineoxidases as a possible mechanism of action of tamoxifen metabolites
Cancer Research·2016
The role of CD109 in glioma progression
European Journal of Cancer·2016
Treating malignant glioma and brain metastasis with nanoparticles: Challenges of a peptide-based targeting and passage through the blood–brain-barrier
European Journal of Cancer·2016
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Frequent Co-authors

Tuomo A. Keinänen(40), Leena Alhonen(39), Alex R. Khomutov(31), Jouko Vepsäläinen(30), Sergey N. Kochetkov(13), Nikolay A. Grigorenko(12), М. А. Хомутов(12), Janne Weisell(12), Juhani Jänne(11), Anne Uimari(10), Marko Pietilä(8), A. R. Simonian(7), Marc Cerrada‐Gimenez(5), Isto Nordback(5), Juhani Sand(5), Eija Pirinen(4), Aki Järvinen(4), Riitta Sinervirta(4), Karl‐Heinz Herzig(4), Thresia Thomas(4)