Sangyoon Y. Ko

University of Toronto — Canada

Neuroscience · Life Sciences

7h-index236citations14works4.62yr avg
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Research Topics

Memory and Neural Mechanisms(7), Neuroscience and Neuropharmacology Research(5), Genetics and Neurodevelopmental Disorders(5), Neurogenesis and neuroplasticity mechanisms(3), Neuroinflammation and Neurodegeneration Mechanisms(3)

Publications14 total

M50. DISRUPTION OF MAJOR PTCHD1 ISOFORMS CAUSES AUTISTIC TRAITS IN SOCIAL BEHAVIOR AND COMMUNICATION
European Neuropsychopharmacology·2025
Systems consolidation reorganizes hippocampal engram circuitry
Nature·2025· 16 cited
Interventionally targeting somatic CAG expansions can be a rapid disease-modifying therapeutic avenue: Preclinical evidence
2025· 1 citedOpen Access
An X-linked long non-coding RNA, PTCHD1-AS, regulates autistic behaviors in humans and in mice
2025Open Access
Genetic variants in DDX53 contribute to autism spectrum disorder associated with the Xp22.11 locus
The American Journal of Human Genetics·2024· 6 citedOpen Access
Genetic variants in <i>DDX53</i> contribute to Autism Spectrum Disorder associated with the Xp22.11 locus
2023· 4 citedOpen Access
Transformation of Hippocampal Memory Engram Cells and the Role of Adult Hippocampal Neurogenesis
TSpace·2023
Neurogenesis-mediated circuit remodeling reduces engram reinstatement and promotes forgetting
2023· 7 citedOpen Access
A shift in the mechanisms controlling hippocampal engram formation during brain maturation
Science·2023· 115 cited
A shift in the mechanisms controlling hippocampal engram formation during brain maturation
2023· 21 citedOpen Access
PTCHD1: Identification and Neurodevelopmental Contributions of an Autism Spectrum Disorder and Intellectual Disability Susceptibility Gene
Genes·2022· 21 citedOpen Access
Neurogenesis-dependent transformation of hippocampal engrams
Neuroscience Letters·2021· 31 cited
Ptchd1 exon3 truncating mutations recapitulate more clinically relevant autistic-like traits in mice
IBRO Reports·2019· 1 citedOpen Access
Activation of the dopamine D1 receptor can extend long-term spatial memory persistence via PKA signaling in mice
Neurobiology of Learning and Memory·2018· 13 citedOpen Access

Frequent Co-authors

Paul W. Frankland(12), Sheena A. Josselyn(5), Adam I. Ramsaran(3), Asim J. Rashid(3), Ankit Awasthi(3), John B. Vincent(3), Marcello Scala(3), Clarrisa A. Bradley(3), Jennifer Howe(3), Brett Trost(3), Nelson Bautista Salazar(3), Carole Shum(3), Miriam S. Reuter(3), Stephen W. Scherer(3), Ali Golbabaei(2), Mitchell L. de Snoo(2), Bi-ru Amy Yeung(2), Jocelyn Lau(2), Lina Tran(2), Andrin Abegg(2)