Lakshman Samala

Lexicon Pharmaceuticals (United States) — United States

Medicine · Health Sciences

7h-index324citations8works0.02yr avg
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Research Topics

Cancer Treatment and Pharmacology(6), Synthetic Organic Chemistry Methods(4), 14-3-3 protein interactions(2), Schizophrenia research and treatment(1), Organometallic Complex Synthesis and Catalysis(1)

Publications8 total

Discovery and Development of LX7101, a Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma
ACS Medicinal Chemistry Letters·2014· 60 citedOpen Access
Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors
Bioorganic & Medicinal Chemistry Letters·2009· 37 citedOpen Access
Modulation of Peripheral Serotonin Levels by Novel Tryptophan Hydroxylase Inhibitors for the Potential Treatment of Functional Gastrointestinal Disorders
Journal of Medicinal Chemistry·2008· 71 citedOpen Access
ChemInform Abstract: The Chemistry of Taxol and Related Taxoids
ChemInform·2002
The Chemistry of Taxol and Related Taxoids
Fortschritte der Chemie Organischer Naturstoffe/Fortschritte der Chemie organischer Naturstoffe/Progress in the chemistry of organic natural products·2002· 58 cited
Synthesis and Biological Evaluation of 2-Acyl Analogues of Paclitaxel (Taxol)
Journal of Medicinal Chemistry·1998· 64 cited
A facile stereocontrolled synthesis of taxol CD rings
Tetrahedron Letters·1994· 17 cited
First and stereocontrolled entry to C-7 hydroxy functionality of taxanes employing boord reaction
Tetrahedron Letters·1994· 17 cited

Frequent Co-authors

Brett Marinelli(3), Terry R. Stouch(3), Alan Wilson(3), David G. I. Kingston(3), Prakash G. Jagtap(3), Zhi-Cai Shi(2), Arokiasamy Devasagayaraj(2), Kunjian Gu(2), Haihong Jin(2), Sheldon Scott(2), Ashok Rao Tunoori(2), Yi Zang(2), S. David Kimball(2), Alan J. Main(2), Weimei Sun(2), Qi Yang(2), Xiang-Qing Yu(2), David R. Powell(2), Qingyun Liu(2), Ravishankar Renduchintala(2)