Richard L. Gourse

University of Wisconsin–Madison — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

66h-index15.1kcitations202works0.02yr avg
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Research Topics

RNA and protein synthesis mechanisms(135), Bacterial Genetics and Biotechnology(129), Bacteriophages and microbial interactions(49), RNA modifications and cancer(41), DNA and Nucleic Acid Chemistry(21)

Publications202 total

Identification and characterization of RNA binding sites for (p)ppGpp using RNA-DRaCALA
Nucleic Acids Research·2023· 4 citedOpen Access
Homologs of the Escherichia coli F Element Protein TraR, Including Phage Lambda Orf73, Directly Reprogram Host Transcription
mBio·2022· 7 citedOpen Access
Rhodobacter sphaeroides CarD Negatively Regulates Its Own Promoter
Journal of Bacteriology·2021· 12 citedOpen Access
CHAPTER 6. Global Regulation of Transcription by Nucleotides and (p)ppGpp
Chemical biology·2021· 1 cited
A majority of <i>Rhodobacter sphaeroides</i> promoters lack a crucial RNA polymerase recognition feature, enabling coordinated transcription activation
Proceedings of the National Academy of Sciences·2020· 24 citedOpen Access
Guanosine Tetraphosphate Has a Similar Affinity for Each of Its Two Binding Sites on Escherichia coli RNA Polymerase
Frontiers in Microbiology·2020· 11 citedOpen Access
Reverse engineering of fatty acid-tolerant Escherichia coli identifies design strategies for robust microbial cell factories
Metabolic Engineering·2020· 39 citedOpen Access
Stepwise Promoter Melting by Bacterial RNA Polymerase
Molecular Cell·2020· 131 citedOpen Access
Deciphering the RNA capping process in bacteria
Proceedings of the National Academy of Sciences·2020· 3 citedOpen Access
E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation
eLife·2019· 79 citedOpen Access
Author response: E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation
2019· 7 citedOpen Access
<i>E. coli</i> TraR allosterically regulates transcription initiation by altering RNA polymerase conformation and dynamics
2019· 2 citedOpen Access
Structural basis for transcription activation by Crl through tethering of σ <sup>S</sup> and RNA polymerase
Proceedings of the National Academy of Sciences·2019· 25 citedOpen Access
Structural basis for transcription activation by Crl through tethering of σ <sup>S</sup> and RNA polymerase
2019Open Access
Genome-wide effects on <i>Escherichia coli</i> transcription from ppGpp binding to its two sites on RNA polymerase
Proceedings of the National Academy of Sciences·2019· 236 citedOpen Access
Transcriptional Responses to ppGpp and DksA
Annual Review of Microbiology·2018· 214 cited
Linking glucose metabolism to the stringent response through the PTS
Proceedings of the National Academy of Sciences·2018· 2 citedOpen Access
DksA and ppGpp Regulate the σ <sup>S</sup> Stress Response by Activating Promoters for the Small RNA DsrA and the Anti-Adapter Protein IraP
Journal of Bacteriology·2017· 59 citedOpen Access
Roles of Transcriptional and Translational Control Mechanisms in Regulation of Ribosomal Protein Synthesis in Escherichia coli
Journal of Bacteriology·2017· 39 citedOpen Access
Dissection of the molecular circuitry controlling virulence in <i>Francisella tularensis</i>
Genes & Development·2017· 42 citedOpen Access
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Frequent Co-authors

Wilma Ross(31), Tamás Gaál(18), David A. Schneider(5), Patricia Sanchez‐Vazquez(5), Richard H. Ebright(4), Sarah E. Aiyar(4), Michio Nomura(3), Brian J. Paul(3), Melanie M. Barker(3), Michael S. Bartlett(3), Shawn T. Estrem(3), Catherine E. Vrentas(3), Albert Y. Chen(3), Justin J. Lemke(3), Khoosheh K. Gosink(2), Julia Salomon(2), Janet T. Newlands(2), Melanie B. Berkmen(2), Shanil P. Haugen(2), J. Alex Appleman(2)