Akshita B. Bhatt

St. Jude Children's Research Hospital — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index139citations17works0.02yr avg
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Research Topics

Melanoma and MAPK Pathways(7), Cancer Cells and Metastasis(6), Cancer-related Molecular Pathways(5), Synthesis and biological activity(3), FOXO transcription factor regulation(3)

Publications17 total

Abstract 2464: Novel models of breast cancer metastasis with different metastatic competence
Cancer Research·2023
Abstract 75: Impaired metastatic seeding underlies concomitant tumor resistance
Cancer Research·2023
ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
Science Advances·2023· 15 citedOpen Access
FISH DIVERSITY OF MAL GAD STREAM NEAR PUROLA TOWN FROM UTTARKASHI DISTRICT, UTTARAKHAND, INDIA
SPIRE - Sciences Po Institutional REpository·2021· 2 citedOpen Access
Constitutive activation of MEK5 promotes a mesenchymal and migratory cell phenotype in triple negative breast cancer
Oncoscience·2021· 3 citedOpen Access
Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple‐negative breast cancer through FRA‐1 regulation
Journal of Cellular Biochemistry·2021· 12 cited
Diverse and converging roles of ERK1/2 and ERK5 pathways on mesenchymal to epithelial transition in breast cancer
Translational Oncology·2021· 16 citedOpen Access
Molecular Mechanisms of Epithelial to Mesenchymal Transition Regulated by ERK5 Signaling
Biomolecules·2021· 27 citedOpen Access
Abstract 5042: Targeting the ERK5 and ERK1/2 pathways simultaneously induces mesenchymal to epithelial transition in TNBC
Cancer Research·2020
ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast Cancer
Frontiers in Oncology·2020· 20 citedOpen Access
Spring 2020 Travel Award Winner
2020
Abstract B078: Inhibition of the MAPK pathways enhances the sensitivity of triple negative breast cancer cells to chemotherapeutic drugs
Molecular Cancer Therapeutics·2019· 1 cited
Pharmacological inhibition of the MEK5/ERK5 and PI3K/Akt signaling pathways synergistically reduces viability in triple‐negative breast cancer
Journal of Cellular Biochemistry·2019· 26 citedOpen Access
Novel Diphenylamine Analogs Induce Mesenchymal to Epithelial Transition in Triple Negative Breast Cancer
Frontiers in Oncology·2019· 17 citedOpen Access
Abstract 1879: Novel diphenylamine analogs induce mesenchymal to epithelial transition and enhance the sensitivity of breast cancer cells to conventional chemotherapeutic agents
Tumor Biology·2019Open Access
Abstract 1879: Novel diphenylamine analogs induce mesenchymal to epithelial transition and enhance the sensitivity of breast cancer cells to conventional chemotherapeutic agents
Cancer Research·2019
Abstract 4204: Structure-activity relationship of diphenylamine derivatives to target epithelial to mesenchymal transition in triple negative breast cancer
Cancer Research·2018

Frequent Co-authors

Matthew E. Burow(12), Patrick T. Flaherty(12), Jane E. Cavanaugh(12), Thomas D. Wright(9), Suravi Chakrabarty(7), Van T. Hoang(6), Margarite D. Matossian(5), Deniz A. Uçar(4), Lucio Miele(4), Mohit Gupta(4), Katie Anna(4), Saloni Patel(3), Steven Elliott(3), Jacqueline La(3), Hope E. Burks(3), Kenneth P. Nephew(3), Bridgette M. Collins‐Burow(3), Van Barnes(3), Myriam Labelle(3), Darlene Monlish(2)