Gina E. Sosinsky

University of California, San Diego — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index6.2kcitations101works0.02yr avg
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Research Topics

Connexins and lens biology(58), Nicotinic Acetylcholine Receptors Study(22), Heat shock proteins research(20), Advanced Electron Microscopy Techniques and Applications(16), Yersinia bacterium, plague, ectoparasites research(10)

Publications101 total

Tuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPP
PLoS Genetics·2016· 34 citedOpen Access
Connexin43 Forms Supramolecular Complexes through Non-Overlapping Binding Sites for Drebrin, Tubulin, and ZO-1
PLoS ONE·2016· 73 citedOpen Access
Spatiotemporal Analysis of the Role that Protein Kinase A Phosphorylation Plays In Gap Junction Assembly
The FASEB Journal·2015
Electron Microscopic Analysis of Lens Gap Junction Connexin50 Hemichannels and Channels
The FASEB Journal·2015
Pannexin2 oligomers localize in the membranes of endosomal vesicles in mammalian cells while Pannexin1 channels traffic to the plasma membrane
Frontiers in Cellular Neuroscience·2015· 48 citedOpen Access
Atomic Force Microscopy Shows Connexin26 Hemichannel Clustering in Purified Membrane Fragments
Biochemistry·2014· 3 cited
The membrane protein Pannexin1 forms two open-channel conformations depending on the mode of activation
Science Signaling·2014· 120 cited
Imaging kinase: connexin43 interactions using phosphorylation activity biosensors and phospho‐specific antibodies (802.2)
The FASEB Journal·2014
Protein Kinase Cδ-mediated Phosphorylation of Connexin43 Gap Junction Channels Causes Movement within Gap Junctions followed by Vesicle Internalization and Protein Degradation
Journal of Biological Chemistry·2014· 45 citedOpen Access
Analysis of Trafficking, Stability and Function of Human Connexin 26 Gap Junction Channels with Deafness-Causing Mutations in the Fourth Transmembrane Helix
PLoS ONE·2013· 44 citedOpen Access
Correlative Light and Electron Microscopic Imaging of Gap Junction Life Cycle Dynamics Using the EM Protein Tags and Phospho-Specific Antibodies
Microscopy and Microanalysis·2013Open Access
Regulation of Connexin26 by Ca2+ and Calmodulin
Biophysical Journal·2013Open Access
A Comparative Antibody Analysis of Pannexin1 Expression in Four Rat Brain Regions Reveals Varying Subcellular Localizations
Frontiers in Pharmacology·2013· 39 citedOpen Access
Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy
Nature Biotechnology·2012· 724 citedOpen Access
Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy
2012
Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation
American Journal of Physiology-Heart and Circulatory Physiology·2012· 106 citedOpen Access
Spatio-Temporal Dissection of Protein Kinase C-Mediated Phosphorylation of the Gap Junction Protein Connexin43
Microscopy and Microanalysis·2012
Preferential electrical coupling regulates neocortical lineage-dependent microcircuit assembly
Nature·2012· 224 citedOpen Access
Picking Faces out of a Crowd
Methods in cell biology·2012· 71 citedOpen Access
Trafficking and Stability of Deafness Mutations in the Fourth Transmembrane Helix of Connexin26 Channels
Biophysical Journal·2012Open Access
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Frequent Co-authors

Mark H. Ellisman(13), Cinzia Ambrosi(10), Thomas J. Deerinck(9), Guido Gaietta(8), Daniela Boassa(8), Atsunori Oshima(6), Gerhard Dahl(5), Bruce J. Nicholson(5), Angela C. Cone(5), David J. DeRosier(4), Amy Smock(4), Galen Hand(4), Noreen R. Francis(3), Feng Qiu(3), Kazutoshi Tani(3), Yoko Hiroaki(3), Yoshinori Fujiyoshi(3), Jennifer Pranskevich(3), John Crum(3), Maryann E. Martone(3)