Euan W. Baxter

University of Leeds — United Kingdom

Medicine · Health Sciences

15h-index935citations23works0.02yr avg
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Research Topics

Cancer-related Molecular Pathways(5), MicroRNA in disease regulation(3), Genomics and Chromatin Dynamics(3), Immunotherapy and Immune Responses(3), Immune Cell Function and Interaction(3)

Publications23 total

Standardized protocols for differentiation of THP-1 cells to macrophages with distinct M(IFNγ+LPS), M(IL-4) and M(IL-10) phenotypes
Journal of Immunological Methods·2020· 209 cited
Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action
Proceedings of the National Academy of Sciences·2017· 41 citedOpen Access
Cocrystal structure of Fc gamma receptor IIIa interacting with Affimer F4, a specific binding protein which blocks IgG binding to the receptor.
2016
A6.05 Optimisation of the THP-1 cell model system for interrogation of differential macrophage polarisation in human disease
Annals of the Rheumatic Diseases·2016· 2 cited
Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis
PLoS ONE·2015· 25 citedOpen Access
Development and characterisation of a 3D multi-cellular<i>in vitro</i>model of normal human breast: a tool for cancer initiation studies
Oncotarget·2015· 32 citedOpen Access
Abstract B127: Loss of miR-92 expression in breast epithelial cells is associated with cancer progression
Molecular Cancer Research·2013· 1 cited
Prior epigenetic priming of cytokine genes in naive T cells is required for their subsequent activation by inducible enhancers
Epigenetics & Chromatin·2013Open Access
The Inducible Tissue-Specific Expression of the Human IL-3/GM-CSF Locus Is Controlled by a Complex Array of Developmentally Regulated Enhancers
The Journal of Immunology·2012· 11 citedOpen Access
FGFR1-Induced Epithelial to Mesenchymal Transition through MAPK/PLCγ/COX-2-Mediated Mechanisms
PLoS ONE·2012· 91 citedOpen Access
The Human IL-3/Granulocyte-Macrophage Colony-Stimulating Factor Locus Is Epigenetically Silent in Immature Thymocytes and Is Progressively Activated during T Cell Development
The Journal of Immunology·2010· 34 citedOpen Access
p53 regulates LIF expression in human medulloblastoma cells
Journal of Neuro-Oncology·2009· 27 cited
A Conserved Insulator That Recruits CTCF and Cohesin Exists between the Closely Related but Divergently Regulated Interleukin-3 and Granulocyte-Macrophage Colony-Stimulating Factor Genes
Molecular and Cellular Biology·2009· 32 citedOpen Access
A Modular Enhancer Is Differentially Regulated by GATA and NFAT Elements That Direct Different Tissue-Specific Patterns of Nucleosome Positioning and Inducible Chromatin Remodeling
Molecular and Cellular Biology·2007· 50 citedOpen Access
Formation of a large, complex domain of histone hyperacetylation at human 14q32.1 requires the serpin locus control region
Nucleic Acids Research·2005· 15 citedOpen Access
RUNX1 transformation of primary embryonic fibroblasts is revealed in the absence of p53
Oncogene·2004· 58 cited
Selection for Loss of p53 Function in T-Cell Lymphomagenesis Is Alleviated by Moloney Murine Leukemia Virus Infection in <i>myc</i> Transgenic Mice
Journal of Virology·2001· 12 citedOpen Access
Identification of murine CBFα1, a runt domain transcription factor, as a putative Myc collaborator in T cell lymphoma
Leukemia·1999· 5 cited
Proviral insertions induce the expression of bone-specific isoforms of PEBP2αA (CBFA1): Evidence for a new <i>myc</i> collaborating oncogene
Proceedings of the National Academy of Sciences·1997· 217 citedOpen Access
p53 and tumour viruses: Catching the guardian off-guard
Trends in Microbiology·1997· 33 cited
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Frequent Co-authors

Ewan R. Cameron(6), Karen Blyth(5), James C. Neil(5), Peter N. Cockerill(5), James Robinson(4), Darren C. Tomlinson(4), Fabio Mirabella(4), David Onions(3), Ann W Morgan(3), Sally James(3), Andrew M. Hanby(3), Valerie Speirs(3), Sarion R. Bowers(3), M. Stewart(2), Astrid Terry(2), Ming Hu(2), Ian Carr(2), Andrew G. Bert(2), Robin L. Owen(2), Maren Thomsen(2)