Sathi Wijeyesinghe

Seattle Children's Hospital — United States

Immunology and Microbiology · Life Sciences

20h-index2.9kcitations44works5.32yr avg
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Research Topics

Immune Cell Function and Interaction(25), T-cell and B-cell Immunology(23), Immunotherapy and Immune Responses(16), CAR-T cell therapy research(7), Single-cell and spatial transcriptomics(6)

Publications44 total

The asthmatic airway generates a dysregulated immune response to rhinovirus infection in a novel pediatric nasal organoid model
Journal of Allergy and Clinical Immunology·2026
Defining the epithelial immune response in rhinovirus-triggered pediatric asthma using human nose organoids 9169
The Journal of Immunology·2025Open Access
LN CD8+ resident memory T cells demonstrate unexpected abundance, exhibit biased migration upon recall, and orchestrate intranodal recall responses 4178
The Journal of Immunology·2025Open Access
Antigen dependency delineates memory and exhausted CD8 T cells 4050
The Journal of Immunology·2025Open Access
Gene therapy for inborn errors of immunity
Annals of Allergy Asthma & Immunology·2025· 5 cited
Deep profiling deconstructs features associated with memory CD8+ T cell tissue residence
Immunity·2024· 32 citedOpen Access
The role of TCR in regulating T cell function in acute and chronic infections and cancer
The Journal of Immunology·2024
Tissue-resident B cells orchestrate macrophage polarisation and function
Nature Communications·2023· 54 citedOpen Access
Chronic antigen in solid tumors drives a distinct program of T cell residence
Science Immunology·2023· 47 citedOpen Access
Tissue-resident memory T cells trigger rapid exudation and local antibody accumulation
Mucosal Immunology·2023· 27 citedOpen Access
Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells
Science Immunology·2022· 67 citedOpen Access
1027 Chronic antigen in solid tumors drives a distinct program of T cell residence
Regular and Young Investigator Award Abstracts·2022· 4 citedOpen Access
Novel Lymphocytic Choriomeningitis Virus Strain Sustains Abundant Exhausted Progenitor CD8 T Cells without Systemic Viremia
The Journal of Immunology·2022· 4 citedOpen Access
Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells
2022· 16 citedOpen Access
Chronic antigen in solid tumors drives a distinct program of T cell residence
The Journal of Immunology·2022
Functional virus-specific memory CD8+ T cells survey glioblastoma
The Journal of Immunology·2022
Correction to: Functional virus‑specific memory T cells survey glioblastoma
Cancer Immunology Immunotherapy·2022· 1 citedOpen Access
Mice with diverse microbial exposure histories as a model for preclinical vaccine testing
Cell Host & Microbe·2021· 73 citedOpen Access
Therapeutic activation of virus-specific resident memory T cells within the glioblastoma microenvironment
2021· 1 citedOpen Access
Cutting Edge: Nucleocapsid Vaccine Elicits Spike-Independent SARS-CoV-2 Protective Immunity
The Journal of Immunology·2021· 165 citedOpen Access
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Frequent Co-authors

David Masopust(40), Vaiva Vezys(23), Clare F. Quarnstrom(14), Pamela C. Rosato(13), J. Michael Stolley(13), Lalit K. Beura(13), Eyob Weyu(13), Stephen D. O’Flanagan(12), Noah Veis Gavil(12), Milcah C. Scott(11), Mark Pierson(8), Andrew G. Soerens(8), Vineet Joag(7), Clark C. Chen(6), Ryan A. Langlois(6), Emily A. Thompson(5), Jason S. Mitchell(5), Marc K. Jenkins(5), Marco Künzli(5), Olivia Smith(5)