Keiko Ozato

National Institutes of Health — United States

Immunology and Microbiology · Life Sciences

103h-index35.6kcitations432works3.62yr avg
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Research Topics

interferon and immune responses(94), T-cell and B-cell Immunology(70), Immune Response and Inflammation(69), Immunotherapy and Immune Responses(69), Cytokine Signaling Pathways and Interactions(66)

Publications432 total

3054 – STAT1–IRF8 TRANSCRIPTION FACTOR CASCADE DEFINES A SPECIALIZED INFLAMMATORY DENDRITIC CELL PROGRAM UPON INTRACELLULAR PATHOGEN INFECTION
Experimental Hematology·2025
IRF8 deficiency causes anxiety-like behavior in a sex-dependent manner
2025Open Access
Integrative single-cell RNA-seq and ATAC-seq identifies transcriptional and epigenetic blueprint guiding osteoclastogenic trajectory
Journal of Bone and Mineral Research·2025· 5 cited
Brd4 expression in CD4 T cells and in microglia promotes neuroinflammation in experimental autoimmune encephalomyelitis
Journal of Neuroinflammation·2025· 2 citedOpen Access
Transcription factors that define the epigenome structures and transcriptomes in microglia
Experimental Hematology·2025· 4 cited
Live cell analysis of mobility and decay kinetics of the histone variant H3.3
Journal of Biological Chemistry·2025· 1 citedOpen Access
Brd4 expression in CD4 T cells and in microglia promotes neuroinflammation in experimental autoimmune encephalomyelitis                                                                                                
2025Open Access
Histone chaperone HIRA facilitates transcription elongation to regulate insulin sensitivity and obesity-associated adipose expansion
2025Open Access
Histone H3.3 ensures cell proliferation and genomic stability during myeloid cell development
2024Open Access
IRF8 defines the epigenetic landscape in postnatal microglia, thereby directing their transcriptome programs
Nature Immunology·2024· 26 cited
BRD4 expression in microglia supports recruitment of T cells into the CNS and exacerbates EAE
2024· 2 citedOpen Access
Igor B. Dawid (1935–2024): A pioneer of developmental and molecular biology
Proceedings of the National Academy of Sciences·2024Open Access
Dynamic and decay kinetics of H3 variants in live cells reveal the pivotal role of HIRA/NSD2 in maintaining the distinct H3.3 specific chromatin landscape
2024Open Access
Bromodomain protein BRD4 directs mitotic cell division of mouse fibroblasts by inhibiting DNA damage
iScience·2024· 8 citedOpen Access
Physical and functional interaction among Irf8 enhancers during dendritic cell differentiation
Cell Reports·2024· 8 citedOpen Access
A single‐cell genomic strategy for alternative transcript start sites identification
Biotechnology Journal·2024· 1 citedOpen Access
Murine IRF8 Mutation Offers New Insight into Osteoclast and Root Resorption
Journal of Dental Research·2024· 7 citedOpen Access
Immature functional development of lumbar locomotor networks in adult Irf8−/− mice
Frontiers in Neuroscience·2024Open Access
Type I IFN Derived from Ly6Chi Monocytes Suppresses Type 2 Inflammation in a Murine Model of Atopic Dermatitis
Journal of Investigative Dermatology·2023· 2 citedOpen Access
Macrophages play a leading role in determining the direction of astrocytic migration in spinal cord injury via ADP-P2Y1R axis
Scientific Reports·2023· 12 citedOpen Access
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Frequent Co-authors

Tomohiko Tamura(11), Anup Dey(7), Moon Kyoo Jang(5), Prafullakumar Tailor(5), David H. Sachs(4), Ettore Appella(4), Hideki Tsujimura(4), Herbert C. Morse(3), Michael S. Marks(3), Paul H. Driggers(3), S L Gleason(3), Akira Nishiyama(3), Kazuki Mochizuki(2), Tsung-Hsien Chang(2), N M Mayer(2), Yuka Kanno(2), Baohong Zhao(2), Lionel B. Ivashkiv(2), Xiaoyu Hu(2), Hee Jeong Kong(2)