Chris S. Rae

Atara Biotherapeutics (United States) — United States

Agricultural and Biological Sciences · Life Sciences

17h-index2.8kcitations38works1.52yr avg
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Research Topics

Plant Virus Research Studies(8), Bacteriophages and microbial interactions(8), Cancer Research and Treatments(8), interferon and immune responses(7), Transgenic Plants and Applications(7)

Publications37 total

Reprogramming <i>Listeria monocytogenes</i> flavin metabolism to improve its therapeutic safety profile and broaden innate T-cell activation
mBio·2025Open Access
ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response
Oncotarget·2025Open Access
NTX250: A Modular mRNA-Based Immunotherapy Platform for HPV-Associated Cancers with Broad Applicability
2025Open Access
Discovery of a Peptoid-Based Nanoparticle Platform for Therapeutic mRNA Delivery via Diverse Library Clustering and Structural Parametrization
ACS Nano·2024· 9 citedOpen Access
Abstract 6725: NTX-470, a novel multispecific T cell engager expressed from mRNA targets PSMA and STEAP1 prostate cancer antigens to generate enhanced functional activity
Cancer Research·2024
Abstract 6536: Enhanced membrane stability of mRNA nanoparticle derived TNFSF14 results in superior T-cell and NK cell stimulation
Cancer Research·2024
Abstract LB346: Mapping of shared tumor antigen reactivity with nanoparticle encapsulated mRNA in prostate cancer patients
Cancer Research·2023
STING controls T cell memory fitness during infection through T cell-intrinsic and IDO-dependent mechanisms
Proceedings of the National Academy of Sciences·2023· 23 citedOpen Access
STING controls T cell memory fitness during infection through T cell intrinsic and IDO dependent mechanisms
2022· 2 citedOpen Access
Abstract 5016: STACT-TREX1: A systemically-administered STING pathway agonist targets tumor-resident myeloid cells and induces adaptive anti-tumor immunity in multiple preclinical models
Cancer Research·2019· 8 cited
Abstract 4782: STACT: A novel tumor-targeting, systemically-administered delivery platform capable of targeting intractable pathways and precise immunomodulation of the tumor microenvironment
Experimental and Molecular Therapeutics·2019
Abstract 5016: STACT-TREX1: A systemically-administered STING pathway agonist targets tumor-resident myeloid cells and induces adaptive anti-tumor immunity in multiple preclinical models
Immunology·2019· 2 cited
Abstract 4782: STACT: A novel tumor-targeting, systemically-administered delivery platform capable of targeting intractable pathways and precise immunomodulation of the tumor microenvironment
Cancer Research·2019
A Potent and Effective Suicidal<i>Listeria</i>Vaccine Platform
Infection and Immunity·2019· 15 citedOpen Access
STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection
Cell Reports·2018· 127 citedOpen Access
Hyper-resolution monitoring of urban flooding with social media and crowdsourcing data
Computers & Geosciences·2017· 222 citedOpen Access
Abstract B50: Synergistic antitumor efficacy in mice with immunotherapy regimens combining recombinant live-attenuated Listeria with immune checkpoint inhibitors
Cancer Immunology Research·2017
Abstract A013: Favorable changes in tumor microenvironment following intravenous dosing with live attenuated <i>Listeria monocytogenes</i>-based immunotherapy
Cancer Immunology Research·2016
Rebalancing Liberalism: Discourse Theory as a Remedy to the Effects of Accelerated Modernity
University Library - University of Saskatchewan (University of Saskatchewan)·2013
The ubiquitin ligase parkin mediates resistance to intracellular pathogens
Nature·2013· 563 citedOpen Access
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Frequent Co-authors

Daniel A. Portnoy(9), Marianne Manchester(9), Meredith L. Leong(8), Weiqun Liu(7), Peter Lauer(6), Justin Skoble(6), Giuseppe Destito(5), Edward E. Lemmens(5), Ole Audun Werner Haabeth(5), Christopher D. Thanos(5), M. G. Finn(4), Maria José González(4), Thomas W. Dubensky(4), Adrienne Sallets(4), Samuel Deutsch(4), Colin J. McKinlay(4), Anastasia M. Makarova(4), Marina Besprozvannaya(4), John Faulhaber(4), Laura Hix Glickman(4)