Sven Kracker

Inserm — France

Immunology and Microbiology · Life Sciences

33h-index4.2kcitations92works4.52yr avg
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Research Topics

Immunodeficiency and Autoimmune Disorders(59), Chronic Lymphocytic Leukemia Research(23), Blood disorders and treatments(21), Immune Cell Function and Interaction(20), T-cell and B-cell Immunology(18)

Publications90 total

Natural history of clinical manifestations in activated phosphoinositide 3-kinase δ syndrome (APDS): Time-to-event analyses using the European Society for Immunodeficiencies-APDS registry
Clinical Immunology·2025Open Access
A heterozygous USB1 variant linked to immunodeficiency
Journal of Human Immunity·2025Open Access
Case Report: Activated PI3-kinase-δ syndrome and ovarian malignancies: a case series from the European ESID-APDS registry
Frontiers in Immunology·2025· 1 citedOpen Access
Comparative efficacy of leniolisib (CDZ173) versus standard of care on rates of respiratory tract infection and serum immunoglobulin M (IgM) levels among individuals with activated phosphoinositide 3-kinase delta (PI3Kδ) syndrome (APDS): an externally controlled study
Clinical & Experimental Immunology·2024· 1 citedOpen Access
Investigating Neutropenia in FNIP1 Deficiency: A CRISPR/Cas9 Model in HL-60 Cells
Blood·2024· 1 citedOpen Access
RAC2 gain-of-function variants causing inborn error of immunity drive NLRP3 inflammasome activation
The Journal of Experimental Medicine·2024· 7 citedOpen Access
Immunoglobulin Class-Switch Recombination Defects
Elsevier eBooks·2024
Loss-of-phosphorylation of IKZF1 results in gain-of-function associated with immune dysregulation
Journal of Allergy and Clinical Immunology·2024· 6 citedOpen Access
A Novel Heterozygous Variant in AICDA Impairs Ig Class Switching and Somatic Hypermutation in Human B Cells and is Associated with Autosomal Dominant HIGM2 Syndrome
Journal of Clinical Immunology·2024· 2 citedOpen Access
Clinical and functional spectrum of RAC2-related immunodeficiency
Blood·2024· 22 citedOpen Access
Rescuing the cytolytic function of APDS1 patient T cells via TALEN-mediated PIK3CD gene correction
Molecular Therapy — Methods & Clinical Development·2023· 4 citedOpen Access
Human inborn errors of immunity associated with IRF4
Frontiers in Immunology·2023· 2 citedOpen Access
A Case Report of Folliculin-Interacting Protein 1 Deficiency
Journal of Clinical Immunology·2023· 3 citedOpen Access
MAGT1 deficiency in XMEN disease is associated with severe platelet dysfunction and impaired platelet glycoprotein N-glycosylation
Journal of Thrombosis and Haemostasis·2023· 11 citedOpen Access
Muller morphs redefined by a multimorphic IRF4 variant presenting as CID with PCP susceptibility
Clinical Immunology·2023
A neomorphic mutation in the interferon activation domain of IRF4 causes a dominant primary immunodeficiency
The Journal of Experimental Medicine·2023· 14 citedOpen Access
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency
Science Immunology·2023· 38 citedOpen Access
Lymphoma as an Exclusion Criteria for CVID Diagnosis Revisited
Journal of Clinical Immunology·2022· 6 cited
Déficits prédominants en anticorps
Elsevier eBooks·2022
UnAIDed Class Switching in Activated B-Cells Reveals Intrinsic Features of a Self-Cleaving IgH Locus
Frontiers in Immunology·2021· 6 citedOpen Access
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Frequent Co-authors

Anne Durandy(30), Alain Fischer(25), Capucine Pïcard(19), Marina Cavazzana(16), Despina Moshous(8), Felipe Suárez(8), Marie‐Céline Deau(6), Lucie Heurtier(6), Bénédicte Neven(6), Nizar Mahlaoui(6), Isabelle André‐Schmutz(6), Loïc Chentout(6), James Curtis(5), Sergey Nejentsev(5), Bodo Grimbacher(5), Kohsuke Imai(5), Frédéric Rieux‐Laucat(5), Julie Bruneau(5), Chantal Lagresle‐Peyrou(5), Tanya Coulter(4)