Paola S. Apaolaza

Helmholtz Zentrum München — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index685citations16works10.82yr avg
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Research Topics

RNA Interference and Gene Delivery(7), Diabetes and associated disorders(7), Virus-based gene therapy research(5), Pancreatic function and diabetes(4), Diabetes Management and Research(3)

Publications16 total

Enterovirus VP1 protein and HLA class I hyperexpression in pancreatic islet cells of organ donors with type 1 diabetes
Diabetologia·2025· 11 citedOpen Access
Quantitative analysis of islet prohormone convertase 1/3 expression in human pancreas donors with diabetes
Diabetologia·2024· 5 citedOpen Access
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 <sup>+</sup> T cell responses
Science Advances·2024· 20 citedOpen Access
New retinoblastoma (<scp>RB</scp>) drug delivery approaches: anti‐tumor effect of atrial natriuretic peptide (<scp>ANP</scp>)‐conjugated hyaluronic‐acid‐coated gold nanoparticles for intraocular treatment of chemoresistant <scp>RB</scp>
Molecular Oncology·2024· 7 citedOpen Access
Coxsackievirus infection induces direct pancreatic β-cell killing but poor anti-viral CD8+ T-cell responses
2023· 4 citedOpen Access
The extent and magnitude of islet T cell infiltration as powerful tools to define the progression to type 1 diabetes
Diabetologia·2023· 23 citedOpen Access
Whole-Slide Image Analysis of Human Pancreas Samples to Elucidate the Immunopathogenesis of Type 1 Diabetes Using the QuPath Software
Frontiers in Molecular Biosciences·2021· 34 citedOpen Access
Islet expression of type I interferon response sensors is associated with immune infiltration and viral infection in type 1 diabetes
Science Advances·2021· 87 citedOpen Access
Hyaluronic acid coating of gold nanoparticles for intraocular drug delivery: Evaluation of the surface properties and effect on their distribution
Experimental Eye Research·2020· 88 cited
Silencing of hepatitis C virus replication by a non-viral vector based on solid lipid nanoparticles containing a shRNA targeted to the internal ribosome entry site (IRES)
Colloids and Surfaces B Biointerfaces·2016· 26 cited
Structural recovery of the retina in a retinoschisin-deficient mouse after gene replacement therapy by solid lipid nanoparticles
Biomaterials·2016· 89 cited
Solid lipid nanoparticle-based vectors intended for the treatment of X-linked juvenile retinoschisis by gene therapy: In vivo approaches in Rs1h-deficient mouse model
Journal of Controlled Release·2015· 56 cited
Solid lipid nanoparticles as non-viral vector for the treatment of chronic hepatitis C by RNA interference
International Journal of Pharmaceutics·2014· 27 cited
Treatment of ocular disorders by gene therapy
European Journal of Pharmaceutics and Biopharmaceutics·2014· 85 cited
Solid Lipid Nanoparticles as Non-Viral Vectors for Gene Transfection in a Cell Model of Fabry Disease
Journal of Biomedical Nanotechnology·2014· 21 cited
A novel gene therapy vector based on hyaluronic acid and solid lipid nanoparticles for ocular diseases
International Journal of Pharmaceutics·2014· 102 cited

Frequent Co-authors

Ana del Pozo‐Rodríguez(7), Alicia Rodríguez‐Gascón(7), Maria Ángelés Solinís(7), Teresa Rodríguez-Calvo(7), Josune Torrecilla(4), Sarah J. Richardson(4), John S. Kaddis(3), Jutta E. Laiho(3), Alberto Pugliese(3), Heikki Hyöty(3), Juan M. Corchado(2), U Friedrich(2), Bernhard H. F. Weber(2), Maike Busch(2), Nicole Dünker(2), Achim Göpferich(2), Diana Balcacean(2), Jose Zapardiel‐Gonzalo(2), Pouria Akhbari(2), Federica Vecchio(2)