Paolo Durigutto

University of Trieste — Italy

Medicine · Health Sciences

24h-index2.1kcitations50works0.52yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(16), Complement system in diseases(15), Systemic Lupus Erythematosus Research(13), Cell Adhesion Molecules Research(8), Rheumatoid Arthritis Research and Therapies(7)

Publications50 total

β2GPI-targeted polymeric nanoparticles form a protective layer to prevent vascular thrombosis in an anti-phospholipid syndrome model
Frontiers in Immunology·2025Open Access
Idarubicin-loaded chitosan nanobubbles to improve survival and decrease drug side effects in hepatocellular carcinoma
Nanomedicine·2025· 1 citedOpen Access
A novel complement-fixing IgM antibody targeting GPC1 as a useful immunotherapeutic strategy for the treatment of pancreatic ductal adenocarcinoma
Journal of Translational Medicine·2023· 2 citedOpen Access
243 Anti-GPC1 IgM activating the complement system is an effective treatment in a pancreatic ductal adenocarcinoma mouse model
Immunobiology·2023
Plasminogen activator-coated nanobubbles targeting cellbound β2-glycoprotein I as a novel thrombus-specific thrombolytic strategy
Haematologica·2022· 12 citedOpen Access
Multiple-Organ Complement Deposition on Vascular Endothelium in COVID-19 Patients
Biomedicines·2021· 68 citedOpen Access
Multi-organ complement deposition in COVID-19 patients
2021· 29 citedOpen Access
Complement Activation and Thrombin Generation by MBL Bound to β2-Glycoprotein I
The Journal of Immunology·2020· 25 citedOpen Access
Targeting CD34+ cells of the inflamed synovial endothelium by guided nanoparticles for the treatment of rheumatoid arthritis
Journal of Autoimmunity·2019· 64 citedOpen Access
New insight into antiphospholipid syndrome: antibodies to β2glycoprotein I-domain 5 fail to induce thrombi in rats
Haematologica·2018· 54 citedOpen Access
Obstetric and vascular antiphospholipid syndrome: same antibodies but different diseases?
Nature Reviews Rheumatology·2018· 138 cited
Targeted Delivery of Neutralizing Anti-C5 Antibody to Renal Endothelium Prevents Complement-Dependent Tissue Damage
Frontiers in Immunology·2017· 25 citedOpen Access
Targeted nanoparticles and complement activation
Molecular Immunology·2017
AB0086 Preventive effects of angiotensin 1-7 on neoangiogenesis and leukocyte trafficking increase in the early phases of an experimental model of antigen induced arthritis
Annals of the Rheumatic Diseases·2017· 1 citedOpen Access
OP0023 Targeted Polymeric Nanoparticles as Diagnostic and Therapeutic Tool for Rheumatoid Arthritis
Annals of the Rheumatic Diseases·2016· 1 cited
FRI0030 Anti-TNF-α Antibody Targeted To Inflamed Synovial Tissue for The Treatment of Rheumatoid Arthritis
Annals of the Rheumatic Diseases·2016
C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation
Nature Communications·2016· 288 citedOpen Access
Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery
Blood·2015· 78 citedOpen Access
Critical Role and Therapeutic Control of the Lectin Pathway of Complement Activation in an Abortion-Prone Mouse Mating
The Journal of Immunology·2015· 33 citedOpen Access
Bispecific antibodies targeting tumor-associated antigens and neutralizing complement regulators increase the efficacy of antibody-based immunotherapy in mice
Leukemia·2014· 79 citedOpen Access
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Frequent Co-authors

Francesco Tedesco(40), Paolo Macor(37), Fabio Fischetti(20), Pier Luigi Meroni(19), Daniele Sblattero(16), Luca De Maso(15), Stefania Biffi(10), Roberta Bulla(9), Fleur Bossi(9), María Orietta Borghi(8), Roberto Marzari(7), Renzo Carretta(7), Chiara Agostinis(6), C. Grossi(6), Chiara Garrovo(6), Claudio Tripodo(5), Federico Colombo(5), Sonia Zorzet(4), Costantino Pitzalis(4), Elena Raschi(4)