Matthew Bjerknes

University of Toronto — Canada

Medicine · Health Sciences

33h-index4.4kcitations69works0.02yr avg
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Research Topics

Cancer Cells and Metastasis(20), Digestive system and related health(16), Gut microbiota and health(9), Genetic factors in colorectal cancer(9), Helicobacter pylori-related gastroenterology studies(6)

Publications69 total

Null mutations of NEUROG3 are associated with delayed-onset diabetes mellitus
JCI Insight·2019· 20 citedOpen Access
The cellular regulators PTEN and BMI1 help mediate NEUROGENIN-3–induced cell cycle arrest
Journal of Biological Chemistry·2019· 11 citedOpen Access
Multiphoton Activation of Photo-Strain-Promoted Azide Alkyne Cycloaddition “Click” Reagents Enables in Situ Labeling with Submicrometer Resolution
Journal of the American Chemical Society·2017· 73 cited
Facile Quenching and Spatial Patterning of Cylooctynes via Strain-Promoted Alkyne–Azide Cycloaddition of Inorganic Azides
Bioconjugate Chemistry·2017· 27 citedOpen Access
804 EDEM3 Controls NEUROGENIN-3 Protein's Half-Life by Inhibiting a Specific Ring Finger E3 Ligase, RNF128 (GRAIL), Attenuated NEUROG3 Degradation
Gastroenterology·2016
Sa2048 Specific NEUROGENIN-3 Domains Induces Cell Cycle Arrest, and Enteroendocrine Differentiation in a Time-Dependent Manner
Gastroenterology·2016
789 A Novel Dominant Negative Frame-Shift Mutation of NEUROGENIN-3 in a Child with Enteric Anendocrinosis
Gastroenterology·2016
epithelium Multipotential stem cells in adult mouse gastric
2016
Origin of the brush cell lineage in the mouse intestinal epithelium
Developmental Biology·2011· 117 citedOpen Access
Cell Lineage metastability in Gfi1-deficient mouse intestinal epithelium
Developmental Biology·2010· 66 cited
Neurogenin 3 and the enteroendocrine cell lineage in the adult mouse small intestinal epithelium
Developmental Biology·2006· 91 cited
Intestinal Epithelial Stem Cells and Progenitors
Methods in enzymology on CD-ROM/Methods in enzymology·2006· 107 cited
Re-examination of P-PTEN staining patterns in the intestinal crypt
Nature Genetics·2005· 18 cited
Gastrointestinal Stem Cells. II. Intestinal stem cells
American Journal of Physiology-Gastrointestinal and Liver Physiology·2005· 137 cited
Multipotential stem cells in adult mouse gastric epithelium
American Journal of Physiology-Gastrointestinal and Liver Physiology·2002· 157 cited
Modulation of specific intestinal epithelial progenitors by enteric neurons
Proceedings of the National Academy of Sciences·2001· 318 citedOpen Access
Colossal Crypts Bordering Colon Adenomas in ApcMin Mice Express Full-Length Apc
American Journal Of Pathology·1999· 21 cited
Clonal analysis of mouse intestinal epithelial progenitors
Gastroenterology·1999· 416 cited
APC mutation and the crypt cycle in murine and human intestine.
PubMed·1997· 51 cited
Clonality of dysplastic epithelium in colorectal adenomas from familial adenomatous polyposis patients.
PubMed·1997· 31 cited
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Frequent Co-authors

Hazel Cheng(41), Hongyun Chen(3), Steven Gallinger(3), Jiafang Wang(3), Martı́n G. Martı́n(3), Ernest Jay(2), Armin Reitmair(2), Mark Redston(2), Kazy Hay(2), Bharati Bapat(2), Tak W. Mak(2), John Totafurno(2), Jack Amar(2), Christopher D. McNitt(2), Vladimir V. Popik(2), Stanley L. Erlandsen(2), R. Sergio Solórzano-Vargas(2), Sujuan Wu(2), Senta Georgia(2), Ravindra Kumar(1)