Alex C. Soupir

Moffitt Cancer Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index314citations78works1.22yr avg
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Research Topics

Single-cell and spatial transcriptomics(25), Gene expression and cancer classification(14), Cancer Genomics and Diagnostics(13), Cancer Immunotherapy and Biomarkers(12), Renal cell carcinoma treatment(12)

Publications79 total

Association of enriched <i>YES1</i> tumor expression at the stromal interface with overall survival in clear cell renal cell carcinoma when treated with first-line immune checkpoint blockade.
Journal of Clinical Oncology·2026
`FastPCA`: An R package for fast singular value decomposition
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
`FastPCA`: An R package for fast singular value decomposition
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
`FastPCA`: An R package for fast singular value decomposition
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
Bayesian multi-cell type models for the analysis of complex immune cell populations with application to ovarian cancer
Briefings in Bioinformatics·2026Open Access
Multicellular immune ecotypes within solid tumors predict real-world therapeutic benefits with immune checkpoint inhibitors
Nature Communications·2025· 3 citedOpen Access
35FGD1 splice variant as a novel biomarker for inferior clinical outcomes and development of brain and bone metastasis in clear cell renal cell carcinoma
The Oncologist·2025Open Access
Spatial clustering of immunosuppressive macrophages in papillary renal cell carcinoma
Kidney Cancer·2025Open Access
Exact Expectation of Complete Spatial Randomness for Nearest Neighbor <i>G</i> ( <i>r</i> ): A Scalable Alternative to Permutations
2025Open Access
Spatial analysis reveals a novel inflammatory tumor transition state which promotes a macrophage-driven induction of sarcomatoid renal cell carcinoma
2025Open Access
scSpatialSIM: a simulator of spatial single-cell molecular data
SoftwareX·2025Open Access
Supplemental Table 2 from Human Immunodeficiency Virus–Associated Differences in the Tumor Immune Microenvironment of Lung, Breast, and Prostate Cancers
2025Open Access
Data from Human Immunodeficiency Virus–Associated Differences in the Tumor Immune Microenvironment of Lung, Breast, and Prostate Cancers
2025Open Access
Supplemental Table 1 from Human Immunodeficiency Virus–Associated Differences in the Tumor Immune Microenvironment of Lung, Breast, and Prostate Cancers
2025Open Access
Supplemental Figure 1 from Human Immunodeficiency Virus–Associated Differences in the Tumor Immune Microenvironment of Lung, Breast, and Prostate Cancers
2025Open Access
spatialGE: Visualization and Analysis of Spatial Heterogeneity in Spatially-Resolved Gene Expression
2025
Genomic, transcriptomic, and immunogenomic landscape of over 1300 sarcomas of diverse histology subtypes
Nature Communications·2025· 5 citedOpen Access
IP16-06  <i>FGD1</i> SPLICE VARIANTS AS PREDICTORS OF BRAIN AND BONE METASTATIC ORGANOTROPISM IN CLEAR CELL RENAL CELL CARCINOMA
The Journal of Urology·2025
Human Immunodeficiency Virus–Associated Differences in the Tumor Immune Microenvironment of Lung, Breast, and Prostate Cancers
Cancer Epidemiology Biomarkers & Prevention·2025Open Access
Supplementary Data S1 from spatialGE Is a User-Friendly Web Application That Facilitates Spatial Transcriptomics Data Analysis
2025Open Access
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Frequent Co-authors

Brooke L. Fridley(28), Oscar E. Ospina(22), Anders Berglund(13), Kenneth Y. Tsai(13), Liang Wang(11), Brandon J. Manley(11), Xiaoqing Yu(10), Mitchell Hayes(10), Inna Smalley(9), Jonathan V. Nguyen(9), Joseph Markowitz(8), Nicholas H. Chakiryan(7), Jordan H. Creed(7), Carlos Moran Segura(7), Brandon J. Manley(6), Roger Li(6), Lauren C. Peres(6), Jodi Balasi(6), Ethan Vallebuona(6), Steven A. Eschrich(6)